Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AGXT | P21549 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15007794 | 0.71 | IDO1 (0.37) | PREPIDO1AGXTKDM4EMAPT | |
| SCHEMBL15007796 | 0.71 | IDO1 (0.37) | PREPIDO1AGXTKDM4EMAPT | |
| SCHEMBL15032475 | 0.70 | NAAA (0.39) | PREPIDO1AGXTKDM4EMAPT | |
| SCHEMBL18287587 | 0.69 | NAAA (0.37) | PREPIDO1AGXTKDM4EMAPT | |
| SCHEMBL2385910 | 0.69 | THRB (0.36) | PREPIDO1AGXTKDM4EMAPT | |
| SCHEMBL12151520 | 0.68 | IDO1 (0.36) | IDO1AGXTKDM4EMAPTNAAA | |
| SCHEMBL15032462 | 0.68 | IDO1 (0.40) | PREPIDO1AGXTNAAAHTT | |
| SCHEMBL29773823 | 0.67 | NAAA (0.44) | IDO1AGXTKDM4EMAPTNAAA | |
| SCHEMBL12151521 | 0.67 | IDO1 (0.37) | IDO1AGXTKDM4EMAPTNAAA | |
| SCHEMBL22639404 | 0.66 | NAAA (0.34) | IDO1AGXTNAAAHTTREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2550285-A1 | TRIOXACARCINS AND USES THEREOF | President and Fellows of Harvard College (US) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011119549-A1 | TRIOXACARCINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2011-09-29 | — | — | WO | disclosed |