Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 11/20 | 0.72 |
| ▸ | NPC1 | O15118 | 10/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528397 | 1.00 | RAB9A (0.72) | RAB9ANPC1MAPTCHKAMEN1 | |
| SCHEMBL31389080 | 1.00 | RAB9A (0.72) | RAB9ANPC1MAPTCHKAMEN1 | |
| SCHEMBL31389079 | 1.00 | RAB9A (0.72) | RAB9ANPC1MAPTCHKAMEN1 | |
| SCHEMBL25528336 | 1.00 | RAB9A (0.72) | RAB9ANPC1MAPTCHKAMEN1 | |
| Hydrochloric Acid SCHEMBL31200518 | 0.99 | RAB9A (0.71) | RAB9ANPC1MAPTCHKAMEN1 | |
| Hydrochloric Acid SCHEMBL25197545 | 0.99 | RAB9A (0.71) | RAB9ANPC1MAPTCHKAMEN1 | |
| Hydrochloric Acid SCHEMBL25218872 | 0.99 | RAB9A (0.71) | RAB9ANPC1MAPTCHKAMEN1 | |
| Hydrochloric Acid SCHEMBL31389072 | 0.99 | RAB9A (0.71) | RAB9ANPC1MAPTCHKAMEN1 | |
| Hydrochloric Acid SCHEMBL25200870 | 0.99 | RAB9A (0.71) | RAB9ANPC1MAPTCHKAMEN1 | |
| Hydrochloric Acid SCHEMBL31419712 | 0.96 | RAB9A (0.69) | RAB9ANPC1MAPTCHKAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250092030-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH | 2025-03-20 | — | — | US | disclosed |
| US-20230203025-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | Sanford Burnham Prebys Medical Discovery Institute | 2023-06-29 | — | — | US | disclosed |
| US-20230203025-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | Sanford Burnham Prebys Medical Discovery Institute | 2023-06-29 | — | — | US | disclosed |
| WO-2023096886-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2023096886-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2023-06-01 | — | — | WO | disclosed |
| WO-2021243230-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250092030-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | PDE2A, GUCY1A1, GCGR | RAB9A 960/4885NPC1 1065/4885MAPT 4474/4885 |
| US-20230203025-A1 | ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A | GPR119, GUCY1A2, PRKG1 | RAB9A 1329/4885NPC1 224/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.