Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.73 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14696832 | 0.87 | CYP1A2 (0.55) | CYP1A2SIRT1RAB9ANPC1POLB | |
| SCHEMBL340809 | 0.85 | CYP1A2 (1.00) | CYP1A2RAB9AFFAR1NPC1POLB | |
| SCHEMBL31136068 | 0.85 | CYP1A2 (1.00) | CYP1A2RAB9AFFAR1NPC1POLB | |
| SCHEMBL14273063 | 0.82 | CYP1A2 (0.73) | CYP1A2RAB9AFFAR1GAAHSD17B10 | |
| SCHEMBL14273049 | 0.81 | CYP1A2 (0.73) | CYP1A2RAB9AFFAR1NPC1POLB | |
| SCHEMBL8174554 | 0.81 | CYP1A2 (0.73) | CYP1A2RAB9AFFAR1NPC1POLB | |
| SCHEMBL8174562 | 0.81 | CYP1A2 (0.73) | CYP1A2RAB9AFFAR1NPC1POLB | |
| SCHEMBL28808652 | 0.80 | CYP1A2 (0.71) | CYP1A2RAB9AFFAR1NPC1POLB | |
| SCHEMBL292247 | 0.80 | KMT2A (0.61) | CYP1A2SIRT1POLBGAAKDM4E | |
| SCHEMBL3356549 | 0.79 | SIRT1 (0.55) | CYP1A2SIRT1HSD17B10KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011104307-A2 | LIGANDS FOR ANTIBODY PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2011-09-01 | — | — | WO | disclosed |
| US-7335466-B2 | Silver salt photothermographic dry imaging material, image recording method and image forming method for the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-02-26 | — | — | US | disclosed |
| US-7335466-B2 | Silver salt photothermographic dry imaging material, image recording method and image forming method for the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2008-02-26 | — | — | US | disclosed |