Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA4 | P22748 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901284 | 0.85 | PTPRG (0.67) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL11729716 | 0.85 | KMT2A (0.64) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL7136041 | 0.83 | KMT2A (0.58) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL6937373 | 0.83 | KMT2A (0.70) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL11724672 | 0.82 | KMT2A (0.65) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL6291181 | 0.82 | KMT2A (0.60) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL910935 | 0.81 | CA2 (0.61) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL28109773 | 0.81 | KMT2A (0.64) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL7389895 | 0.81 | PTPRG (0.51) | KMT2AMEN1POLBALDH1A1CYP2C9 | |
| SCHEMBL911071 | 0.81 | MEN1 (0.64) | KMT2AMEN1POLBALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105646396-B | A kind of synthetic method of benzothiazole derivant | 上海应用技术学院 | 2018-09-14 | — | — | CN | claimed |
| CN-105646396-A | Method for synthesizing benzothiazole derivatives | 上海应用技术学院 | 2016-06-08 | — | — | CN | claimed |
| EP-0649649-A2 | Colloidal, dispersible formulations of active substances | BAYER AG (DE) | 1995-04-26 | — | — | EP | claimed |
| CN-105646396-B | A kind of synthetic method of benzothiazole derivant | 上海应用技术学院 | 2018-09-14 | — | — | CN | disclosed |
| CN-105646396-A | Method for synthesizing benzothiazole derivatives | 上海应用技术学院 | 2016-06-08 | — | — | CN | disclosed |
| CN-105646396-A | Method for synthesizing benzothiazole derivatives | 上海应用技术学院 | 2016-06-08 | — | — | CN | disclosed |
| CN-104140386-A | Method for preparing 2-benzyl-isothiourea trifluoroacetate | SHANGHAI INST TECHNOLOGY | 2014-11-12 | — | — | CN | disclosed |
| EP-2064196-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2012-03-14 | — | — | EP | disclosed |
| US-8119568-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest II | BASF SE (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8017554-B2 | 3-amino-1,2-benzisothiazole compounds for combating animal pest | BASF SE (DE) | 2011-09-13 | — | — | US | disclosed |
| US-7868017-B2 | 9-azabicyclo[3.3.1]nonane derivatives | N.V. ORGANON (NL) | 2011-01-11 | — | — | US | disclosed |
| US-20100167922-A1 | 3-Amino-1,2-benzisothiazole Compounds for Combating Animal Pest | BASF SE (DE) | 2010-07-01 | — | — | US | disclosed |
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BASF SE (DE) | 2010-01-14 | — | — | US | disclosed |
| EP-2003975-B1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2009-11-18 | — | — | EP | disclosed |
| EP-2064196-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF Aktiengesellschaft (DE) | 2009-06-03 | — | — | EP | disclosed |
| EP-2003975-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2008-12-24 | — | — | EP | disclosed |
| WO-2008090048-A2 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST II | BASF SE (DE) | 2008-07-31 | — | — | WO | disclosed |
| WO-2007113119-A1 | 3-AMINO-1,2-BENZISOTHIAZOLE COMPOUNDS FOR COMBATING ANIMAL PEST | BASF SE (DE) | 2007-10-11 | — | — | WO | disclosed |
| US-20070112019-A1 | 9-Azabicyclo[3.3.1]nonane derivatives | N.V. ORGANON (NL) | 2007-05-17 | — | — | US | disclosed |
| EP-0111442-A1 | N-2-heterocyclyl-phenylsulfonyl-N'-pyrimidinyl and like triazinyl urea | CIBA-GEIGY AG (CH) | 1984-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009848-A1 | 3-Amino-1,2-Benzisothiazole Compounds for Combating Animal Pest II | BPNT1, BCAT1, TGFBR1 | KMT2A 2749/4885MEN1 3020/4885POLB 4431/4885 |
| US-20100167922-A1 | 3-Amino-1,2-benzisothiazole Compounds for Combating Animal Pest | BPNT1, AADAT, BCAT1 | KMT2A 872/4885MEN1 1368/4885POLB 4751/4885 |
| US-20070112019-A1 | 9-Azabicyclo[3.3.1]nonane derivatives | AZI2, TPMT, TET3 | KMT2A 844/4885MEN1 1510/4885POLB 649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.