Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.50 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.50 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.50 |
| ▸ | GBA1 | P04062 | 6/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.37 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.37 |
| ▸ | GUSB | P08236 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699372 | 0.93 | GNAI3 (0.41) | GNAI3GNAO1GNAI1GBA1S1PR4 | |
| SCHEMBL25590730 | 0.90 | GNAI3 (0.47) | GNAI3GNAO1GNAI1S1PR4S1PR1 | |
| SCHEMBL31066862 | 0.89 | GNAI3 (0.58) | GNAI3GNAO1GNAI1GBA1S1PR4 | |
| SCHEMBL26042870 | 0.89 | GNAI3 (0.58) | GNAI3GNAO1GNAI1GBA1S1PR4 | |
| SCHEMBL21949297 | 0.89 | GNAI3 (0.58) | GNAI3GNAO1GNAI1GBA1S1PR4 | |
| SCHEMBL24803090 | 0.89 | GNAI3 (0.58) | GNAI3GNAO1GNAI1GBA1S1PR4 | |
| SCHEMBL31066880 | 0.89 | GNAI3 (0.58) | GNAI3GNAO1GNAI1GBA1S1PR4 | |
| SCHEMBL31066865 | 0.89 | GNAI3 (0.58) | GNAI3GNAO1GNAI1GBA1S1PR4 | |
| SCHEMBL25448549 | 0.87 | GNAI3 (0.55) | GNAI3GNAO1GNAI1GBA1S1PR4 | |
| SCHEMBL23641956 | 0.85 | MEN1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242923-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2021-12-02 | — | — | WO | disclosed |