Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 5/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 5/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | VCP | P55072 | 1/20 | 0.34 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.34 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.34 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072425 | 0.93 | GNAI3 (0.50) | GNAI3GNAO1GNAI1S1PR4S1PR1 | |
| SCHEMBL11577474 | 0.88 | GNAI3 (0.39) | GNAI3GNAO1GNAI1CYP2C9HRH3 | |
| SCHEMBL13301319 | 0.88 | GNAI3 (0.47) | GNAI3GNAO1GNAI1NCF1CYP2C9 | |
| SCHEMBL20210155 | 0.88 | MEN1 (0.38) | NCF1MEN1KMT2AMITFHRH4 | |
| SCHEMBL9698093 | 0.88 | MEN1 (0.38) | NCF1MEN1KMT2AMITFHRH4 | |
| SCHEMBL23641956 | 0.88 | MEN1 (0.38) | NCF1MEN1KMT2AMITFHRH4 | |
| SCHEMBL15806956 | 0.83 | MEN1 (0.37) | NCF1MEN1KMT2AMITFHRH4 | |
| SCHEMBL25448549 | 0.82 | GNAI3 (0.55) | GNAI3GNAO1GNAI1MEN1KMT2A | |
| SCHEMBL25590730 | 0.82 | GNAI3 (0.47) | GNAI3GNAO1GNAI1S1PR4S1PR1 | |
| SCHEMBL24803090 | 0.81 | GNAI3 (0.58) | GNAI3GNAO1GNAI1S1PR4S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3368519-B1 | NOVEL HETEROCYCLIC ANTIESTROGENS | SUN PHARMA ADVANCED RES CO LTD (IN) | 2022-04-06 | — | — | EP | disclosed |
| WO-2021019514-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF | INTEGRAL BIOSCIENCES PVT. LTD. (IN) | 2021-02-04 | — | — | WO | disclosed |
| EP-2125748-B1 | ACYLAMINOPYRAZOLES AS FGFR INHIBITORS | ASTRAZENECA AB (SE) | 2011-05-25 | — | — | EP | disclosed |
| US-5109013-A | 2-(2-substituted aminoethyl)-1,4-dialkyl-3,4-dihydro-1H-1,3,5]triazepino[3,2-a]benzimidazol-5(2H)-ones as muscle relaxants | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-04-28 | — | — | US | disclosed |