Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.57 |
| ▸ | PI4KA | P42356 | 1/20 | 0.57 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.57 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 7/20 | 0.55 |
| ▸ | EGFR | P00533 | 7/20 | 0.55 |
| ▸ | CDK1 | P06493 | 3/20 | 0.55 |
| ▸ | ABL1 | P00519 | 5/20 | 0.50 |
| ▸ | KDR | P35968 | 4/20 | 0.50 |
| ▸ | ABL2 | P42684 | 4/20 | 0.50 |
| ▸ | PIK3CD | O00329 | 10/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.46 |
| ▸ | HCK | P08631 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24072905 | 0.83 | SRC (0.50) | PI4KBPI4KAPI4K2BPI4K2ASRC | |
| SCHEMBL29484520 | 0.83 | PI4KB (0.57) | PI4KBPI4KAPI4K2BPI4K2ASRC | |
| SCHEMBL16236479 | 0.83 | PI4KB (0.57) | PI4KBPI4KAPI4K2BPI4K2ASRC | |
| Ammonia Solution, Strong SCHEMBL30181004 | 0.81 | PI4KB (0.54) | PI4KBPI4KAPI4K2BPI4K2ASRC | |
| SCHEMBL26813955 | 0.76 | SRC (0.47) | PI4KBPI4KAPI4K2BPI4K2ASRC | |
| SCHEMBL26813988 | 0.75 | SRC (0.46) | SRCEGFRCDK1ABL1KDR | |
| SCHEMBL30180822 | 0.74 | SRC (0.55) | PI4KBPI4KAPI4K2BPI4K2ASRC | |
| SCHEMBL23966673 | 0.74 | SRC (0.55) | PI4KBPI4KAPI4K2BPI4K2ASRC | |
| SCHEMBL27217632 | 0.73 | SRC (0.48) | PI4KBPI4KAPI4K2BPI4K2ASRC | |
| SCHEMBL30813603 | 0.73 | SRC (0.48) | PI4KBPI4KAPI4K2BPI4K2ASRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242505-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2021-12-02 | — | — | WO | disclosed |