Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 4/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PI4KA | P42356 | 1/20 | 0.44 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.44 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.44 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19264154 | 0.85 | SRC (0.67) | SRCEGFRCDK1ADKMEN1 | |
| SCHEMBL24072610 | 0.84 | SRC (0.50) | SRCPIK3CDEGFRCDK1ADK | |
| SCHEMBL24072588 | 0.83 | PI4KB (0.57) | SRCCYP2E1CYP2A6CYP3A4PI4KA | |
| SCHEMBL22084739 | 0.83 | SRC (0.50) | SRCCYP2E1CYP2A6CYP3A4PI4KA | |
| SCHEMBL29484482 | 0.83 | SRC (0.50) | SRCCYP2E1CYP2A6CYP3A4PI4KA | |
| SCHEMBL30150810 | 0.80 | SRC (0.80) | SRCEGFRCDK1MEN1KMT2A | |
| SCHEMBL30150807 | 0.80 | SRC (0.80) | SRCEGFRCDK1MEN1KMT2A | |
| SCHEMBL22086027 | 0.80 | SRC (0.80) | SRCEGFRCDK1MEN1KMT2A | |
| SCHEMBL22086335 | 0.78 | SRC (0.39) | SRCEGFRCDK1ADKMEN1 | |
| SCHEMBL22086067 | 0.76 | SRC (0.78) | SRCEGFRCDK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242505-A1 | INHIBITORS OF NEK7 KINASE | Halia Therapeutics, Inc. (US) | 2021-12-02 | — | — | WO | disclosed |