Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179020 | 0.87 | NPC1 (0.63) | HDAC1HDAC2HDAC8RAB9ANPC1 | |
| SCHEMBL2408888 | 0.86 | RAB9A (0.77) | HDAC1HDAC2HDAC8RAB9ANPC1 | |
| Piperonylic Acid SCHEMBL4741337 | 0.84 | RAB9A (0.59) | HDAC1HDAC8RAB9ANPC1KMT2A | |
| SCHEMBL4991221 | 0.81 | HDAC1 (0.63) | HDAC1HDAC2HDAC8RAB9ANPC1 | |
| SCHEMBL2408431 | 0.81 | RAB9A (0.73) | HDAC1HDAC2RAB9ANPC1KMT2A | |
| SCHEMBL6781831 | 0.80 | HSP90AA1 (0.82) | HDAC1HDAC2NPC1KMT2AHDAC6 | |
| SCHEMBL107323 | 0.78 | RAB9A (0.81) | HDAC1RAB9ANPC1KMT2AHDAC6 | |
| SCHEMBL2405328 | 0.78 | MCHR1 (0.60) | HDAC1HDAC2HDAC8KMT2AHDAC6 | |
| SCHEMBL179083 | 0.78 | LMNA (0.64) | HDAC1HDAC2HDAC8RAB9ANPC1 | |
| SCHEMBL24513888 | 0.78 | NPC1 (0.67) | RAB9ANPC1KMT2AHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |