Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 13/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 3/20 | 1.00 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.64 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.64 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 1/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2403826 | 0.86 | MPO (1.00) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL517983 | 0.85 | MPO (0.73) | MPOSLC6A4HTR1AHTR2ATRPM8 | |
| SCHEMBL29571866 | 0.85 | MPO (0.73) | MPOSLC6A4HTR1AHTR2ATRPM8 | |
| SCHEMBL2405001 | 0.84 | MPO (1.00) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL1970036 | 0.82 | MPO (0.70) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL2405551 | 0.82 | MPO (0.75) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL4352009 | 0.82 | MPO (0.74) | MPOSLC6A4HTR1AHTR2ATRPM8 | |
| SCHEMBL2404556 | 0.82 | MPO (0.71) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL2408407 | 0.82 | MPO (0.71) | MPOSLC6A4NOTUMMTNR1AMTNR1B | |
| SCHEMBL2405192 | 0.81 | NOTUM (0.73) | MPOSLC6A4NOTUMMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | MPO 3915/4885SLC6A4 781/4885NOTUM 3663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.