Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.73 |
| ▸ | MPO | P05164 | 14/20 | 0.70 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.68 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.65 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.65 |
| ▸ | SPR | P35270 | 1/20 | 0.59 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.58 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405088 | 0.85 | MPO (0.67) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL2405350 | 0.84 | MPO (0.65) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL2407287 | 0.81 | MPO (1.00) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL3695233 | 0.81 | MPO (1.00) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL2410329 | 0.80 | MPO (1.00) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL20242784 | 0.80 | NOTUM (0.78) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL2405001 | 0.80 | MPO (1.00) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL32678266 | 0.80 | NOTUM (0.77) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL32678263 | 0.80 | NOTUM (0.77) | NOTUMMPOSLC6A4MTNR1AMTNR1B | |
| SCHEMBL2177075 | 0.79 | TSHR (0.75) | NOTUMMPOSLC6A4MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | ACTELION PHARMACEUTICALS LTD. (CH) | 2011-09-01 | — | — | US | disclosed |
| CN-102164896-A | Phenethylamide derivatives and their heterocyclic analogues | ACTELION PHARMACEUTICALS LTD | 2011-08-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212968-A1 | PHENETHYLAMIDE DERIVATIVES AND THEIR HETEROCYCLIC ANALOGUES | HCRTR2, HCRTR1, HRH3 | NOTUM 3663/4885MPO 3915/4885SLC6A4 781/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.