Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24073286 | 0.83 | HDAC3 (0.40) | LPAR1LPAR5KMT2AMEN1 | |
| SCHEMBL15223936 | 0.79 | ALDH1A1 (0.54) | ALDH1A1ALDH2LPAR1LPAR5KMT2A | |
| SCHEMBL2570247 | 0.75 | ALDH1A1 (0.52) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT | |
| SCHEMBL14861373 | 0.74 | TDP1 (0.48) | ALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL4233493 | 0.74 | ALDH1A1 (0.52) | ALDH1A1ALDH2LPAR1LPAR5 | |
| SCHEMBL5374120 | 0.74 | CA12 (0.50) | ALDH1A1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL5185961 | 0.73 | LOXL2 (0.58) | ALDH1A1LPAR1LPAR5KMT2ASMN1; SMN2 | |
| SCHEMBL4178296 | 0.73 | RARB (0.58) | ALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6924817 | 0.72 | KCNH2 (0.43) | ALDH1A1KMT2AMEN1MAPT | |
| Terephthalic Acid SCHEMBL10444567 | 0.72 | TSHR (0.62) | ALDH1A1KMT2ASMN1; SMN2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242923-A1 | TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | AXIAL THERAPEUTICS, INC. (US) | 2021-12-02 | — | — | WO | disclosed |