Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLQ | O75417 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074689 | 0.89 | MAPK14 (0.48) | MAPTKDM4EALDH1A1KMT2ARAB9A | |
| SCHEMBL24072281 | 0.86 | LRRK2 (0.48) | MAPTKDM4ELRRK2ALDH1A1LMNA | |
| SCHEMBL25063120 | 0.82 | STAT3 (0.57) | MAPTLRRK2ALDH1A1LMNAMAPK1 | |
| SCHEMBL24072715 | 0.77 | TRPV1 (0.45) | MAPTKDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL24072749 | 0.77 | STAT3 (0.41) | MAPTKDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL24072763 | 0.76 | ADORA2A (0.43) | ALDH1A1LMNAKMT2AMEN1RAB9A | |
| SCHEMBL24072759 | 0.76 | CDK2 (0.40) | MAPTALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL24072769 | 0.76 | POLQ (0.41) | MAPTKDM4EALDH1A1LMNAPOLQ | |
| SCHEMBL24072717 | 0.75 | KDR (0.44) | MAPTKDM4EALDH1A1POLQRAB9A | |
| SCHEMBL24074429 | 0.74 | RAB9A (0.52) | MAPTKDM4EALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-02-29 | — | — | US | disclosed |
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240066136-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | DDB1, DCLRE1A, MDM2 | MAPT 3010/4885KDM4E 786/4885LRRK2 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.