Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 9/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | POLQ | O75417 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 4/20 | 0.46 |
| ▸ | JAK1 | P23458 | 4/20 | 0.46 |
| ▸ | TYK2 | P29597 | 4/20 | 0.46 |
| ▸ | JAK3 | P52333 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074432 | 0.88 | MAPK14 (0.49) | KMT2AMAPTALDH1A1KDM4ERAB9A | |
| SCHEMBL24074387 | 0.86 | MAPT (0.48) | LRRK2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL25063120 | 0.84 | STAT3 (0.57) | LRRK2KMT2AMEN1MAPTALDH1A1 | |
| SCHEMBL24073698 | 0.78 | STAT3 (0.52) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL18412769 | 0.77 | MAPT (0.56) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL24073701 | 0.76 | POLQ (0.47) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL24072284 | 0.75 | ADORA2A (0.44) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL24072273 | 0.74 | TP53 (0.48) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL24072346 | 0.74 | STAT3 (0.41) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL24072271 | 0.74 | ITK (0.43) | ALDH1A1LMNAPOLQRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239117-A1 | MODIFIED PROTEINS AND PROTEIN DEGRADERS | CULLGEN (SHANGHAI) , INC. (CN) | 2021-12-02 | — | — | WO | disclosed |