Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.44 |
| ▸ | PRF1 | P14222 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15120762 | 0.87 | MAPT (0.46) | APPMAPTMEN1KMT2ATHRB | |
| SCHEMBL14930761 | 0.87 | MAPT (0.46) | APPMAPTMEN1KMT2ATHRB | |
| SCHEMBL20621189 | 0.87 | MAPT (0.46) | APPMAPTMEN1KMT2ATHRB | |
| SCHEMBL15096136 | 0.86 | MAPT (0.47) | APPESR1ESR2MAPTMEN1 | |
| SCHEMBL14827729 | 0.85 | APP (0.50) | APPESR1ESR2MAPTMEN1 | |
| SCHEMBL17966395 | 0.83 | APP (0.50) | APPESR1ESR2MAPTMEN1 | |
| SCHEMBL15099537 | 0.82 | APP (0.56) | APPMAPTPRF1KDM4EALDH1A1 | |
| SCHEMBL16532192 | 0.82 | MAPT (0.51) | APPMAPTMEN1KMT2AHSD17B1 | |
| SCHEMBL14762765 | 0.81 | MAPT (0.61) | APPESR1ESR2MAPTMEN1 | |
| SCHEMBL30758529 | 0.78 | NQO2 (0.53) | APPMAPTPRF1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200300844-A1 | METHODS, SYSTEMS AND DEVICES FOR DETECTING INFLAMMATION | UNIV STELLENBOSCH (ZA) | 2020-09-24 | — | — | US | claimed |
| EP-2538982-A1 | PET MONITORING OF AB-DIRECTED IMMUNOTHERAPY | Janssen Alzheimer Immunotherapy (IE) | 2013-01-02 | — | — | EP | claimed |
| WO-2011106732-A1 | PET MONITORING OF AB-DIRECTED IMMUNOTHERAPY | WYETH LLC (US) | 2011-09-01 | — | — | WO | claimed |
| EP-3710835-B1 | METHOD OF DETECTING INFLAMMATION | UNIV STELLENBOSCH (ZA) | 2026-03-11 | — | — | EP | disclosed |
| US-12522760-B2 | Photoinduced thermochromic or thermoluminescent composition | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (CSIC) (ES) | 2026-01-13 | — | — | US | disclosed |
| US-12385904-B2 | Method of detecting inflammation | STELLENBOSCH UNIVERSITY (ZA) | 2025-08-12 | — | — | US | disclosed |
| EP-4191518-A1 | METHODS AND APPARATUS FOR DISPLAYING ENHANCED IMAGING DATA ON A CLINICAL IMAGE | Intuitive Surgical Operations, Inc. (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20220348811-A1 | PHOTOINDUCED THERMOCHROMIC OR THERMOLUMINESCENT COMPOSITION | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2022-11-03 | — | — | US | disclosed |
| EP-4069798-A1 | A PHOTOINDUCED THERMOCHROMIC OR THERMOLUMINESCENT COMPOSITION | Consejo Superior de Investigaciones Científicas (CSIC) (ES) | 2022-10-12 | — | — | EP | disclosed |
| EP-3731176-B1 | METHODS AND APPARATUS FOR DISPLAYING ENHANCED IMAGING DATA ON A CLINICAL IMAGE | INTUITIVE SURGICAL OPERATIONS (US) | 2021-11-17 | — | — | EP | disclosed |
| WO-2021110794-A1 | A PHOTOINDUCED THERMOCHROMIC OR THERMOLUMINESCENT COMPOSITION | CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) | 2021-06-10 | — | — | WO | disclosed |
| EP-3710835-A1 | METHOD OF DETECTING INFLAMMATION | Stellenbosch University (ZA) | 2020-09-23 | — | — | EP | disclosed |
| EP-3710834-A1 | METHODS, SYSTEMS AND DEVICES FOR DETECTING INFLAMMATION | Stellenbosch University (ZA) | 2020-09-23 | — | — | EP | disclosed |
| EP-3109822-A1 | METHODS AND APPARATUS FOR DISPLAYING ENHANCED IMAGING DATA ON A CLINICAL IMAGE | Intuitive Surgical Operations, Inc. (US) | 2016-12-28 | — | — | EP | disclosed |
| EP-2486540-B1 | METHODS AND APPARATUS FOR DISPLAYING ENHANCED IMAGING DATA ON A CLINICAL IMAGE | INTUITIVE SURGICAL OPERATIONS (US) | 2016-09-07 | — | — | EP | disclosed |
| US-20130084245-A1 | PET MONITORING OF A-BETA-DIRECTED IMMUNOTHERAPY | WYETH LLC (US) | 2013-04-04 | — | — | US | disclosed |
| EP-2538982-A1 | PET MONITORING OF AB-DIRECTED IMMUNOTHERAPY | Janssen Alzheimer Immunotherapy (IE) | 2013-01-02 | — | — | EP | disclosed |
| WO-2011106732-A1 | PET MONITORING OF AB-DIRECTED IMMUNOTHERAPY | WYETH LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011106732-A1 | PET MONITORING OF AB-DIRECTED IMMUNOTHERAPY | WYETH LLC (US) | 2011-09-01 | — | — | WO | disclosed |
| US-20090087376-A1 | Heterocyclic Dye Compounds For In Vivo Imaging And Diagnosis Of Alzheimer's Disease | THE GENERAL HOSPITAL CORPORATION (US) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090087376-A1 | Heterocyclic Dye Compounds For In Vivo Imaging And Diagnosis Of Alzheimer's Disease | APP, PSEN1, BACE1 | APP 1/4885ESR1 3229/4885ESR2 2889/4885 |
| US-20130084245-A1 | PET MONITORING OF A-BETA-DIRECTED IMMUNOTHERAPY | APBA1, APP, BACE1 | APP 2/4885ESR1 4393/4885ESR2 2373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.