Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 8/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | APEX1 | P27695 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20718538 | 0.93 | MAPT (0.56) | APPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL28643094 | 0.90 | MAPT (0.52) | APPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL15096136 | 0.84 | MAPT (0.47) | APPMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL2407500 | 0.82 | APP (0.53) | APPMAPTKDM4EALDH1A1NPSR1 | |
| SCHEMBL15120762 | 0.82 | MAPT (0.46) | APPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL20621189 | 0.82 | MAPT (0.46) | APPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL14930761 | 0.82 | MAPT (0.46) | APPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL7011753 | 0.81 | MAPT (0.55) | APPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL15859153 | 0.80 | MAPT (0.62) | APPMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL14730340 | 0.80 | MAPT (0.62) | APPMAPTKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210017262-A1 | BLOOD-BRAIN BARRIER PERMEABLE PEPTIDE COMPOSITIONS | ICB INT INC (US) | 2021-01-21 | — | — | US | disclosed |
| US-20140193834-A1 | BLOOD-BRAIN BARRIER PERMEABLE PEPTIDE COMPOSITIONS | ICB INTERNATIONAL, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20130177568-A1 | BLOOD-BRAIN BARRIER PERMEABLE PEPTIDE COMPOSITIONS | ICB INTERNATIONAL, INC. (US) | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210017262-A1 | BLOOD-BRAIN BARRIER PERMEABLE PEPTIDE COMPOSITIONS | FCGR2A, VSIR, FCGR3B | APP 4/4885MAPT 28/4885KDM4E 4327/4885 |
| US-20130177568-A1 | BLOOD-BRAIN BARRIER PERMEABLE PEPTIDE COMPOSITIONS | FCGR2A, VSIR, FCGR3B | APP 4/4885MAPT 28/4885KDM4E 4327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.