Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | APP | P05067 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2407500 | 0.86 | APP (0.53) | MAPTAPPALDH1A1MEN1KMT2A | |
| SCHEMBL20621189 | 0.85 | MAPT (0.46) | MAPTAPPALDH1A1MEN1KMT2A | |
| SCHEMBL15120762 | 0.85 | MAPT (0.46) | MAPTAPPALDH1A1MEN1KMT2A | |
| SCHEMBL14930761 | 0.85 | MAPT (0.46) | MAPTAPPALDH1A1MEN1KMT2A | |
| SCHEMBL15099537 | 0.84 | APP (0.56) | MAPTAPPALDH1A1LMNANPSR1 | |
| SCHEMBL16706031 | 0.83 | KMT2A (0.48) | MAPTAPPALDH1A1MEN1KMT2A | |
| SCHEMBL17966395 | 0.81 | APP (0.50) | MAPTAPPALDH1A1MEN1KMT2A | |
| SCHEMBL16532192 | 0.81 | MAPT (0.51) | MAPTAPPALDH1A1MEN1KMT2A | |
| SCHEMBL14762765 | 0.80 | MAPT (0.61) | MAPTAPPALDH1A1MEN1KMT2A | |
| SCHEMBL19073256 | 0.80 | MAPT (0.37) | MAPTAPPALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8890126-B2 | Compound for optoelectronic device, organic light emitting diode including the same, and display including the organic light emitting diode | CHEIL INDUSTRIES, INC. (KR) | 2014-11-18 | — | — | US | disclosed |
| US-20140193834-A1 | BLOOD-BRAIN BARRIER PERMEABLE PEPTIDE COMPOSITIONS | ICB INTERNATIONAL, INC. (US) | 2014-07-10 | — | — | US | disclosed |
| US-20130177568-A1 | BLOOD-BRAIN BARRIER PERMEABLE PEPTIDE COMPOSITIONS | ICB INTERNATIONAL, INC. (US) | 2013-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130177568-A1 | BLOOD-BRAIN BARRIER PERMEABLE PEPTIDE COMPOSITIONS | FCGR2A, VSIR, FCGR3B | MAPT 28/4885APP 4/4885ALDH1A1 4799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.