Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | RAB9A | P51151 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.43 |
| ▸ | RELA | Q04206 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075112 | 0.88 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL24075884 | 0.87 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL30454863 | 0.86 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL24075885 | 0.86 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL24075714 | 0.85 | KDM4E (0.46) | NPC1RAB9ASMN1; SMN2LMNAMAPT | |
| SCHEMBL24090463 | 0.84 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL24075711 | 0.84 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL24075715 | 0.83 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL24075115 | 0.79 | PKM (0.50) | NPC1RAB9ASMN1; SMN2LMNAPOLB | |
| SCHEMBL24075117 | 0.78 | KDM4E (0.54) | NPC1RAB9ASMN1; SMN2LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121574131-A | Heterocyclic compounds for insect repellent | 勃林格殷格翰动物保健有限公司 | 2026-02-27 | — | — | CN | disclosed |
| US-12312356-B2 | Anthelmintic heterocyclic compounds | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2025-05-27 | — | — | US | disclosed |
| US-20240166653-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2024-05-23 | — | — | US | disclosed |
| US-11964977-B2 | Anthelmintic heterocyclic compounds | Boehringer Ingelheim Animal Health USA Inc. (US) | 2024-04-23 | — | — | US | disclosed |
| CN-116249704-A | Heterocyclic compounds for insect repellent | 勃林格殷格翰动物保健美国公司 | 2023-06-09 | — | — | CN | disclosed |
| EP-4185589-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-05-31 | — | — | EP | disclosed |
| US-20210380591-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-09 | — | — | US | disclosed |
| US-20210380591-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-09 | — | — | US | disclosed |
| WO-2021242581-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-02 | — | — | WO | disclosed |
| WO-2021242581-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11964977-B2 | Anthelmintic heterocyclic compounds | AADAC, HNMT, HRH4 | NPC1 1209/4885RAB9A 1017/4885SMN1; SMN2 3947/4885 |
| US-20240166653-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | AADAC, HNMT, HRH4 | NPC1 1209/4885RAB9A 1017/4885SMN1; SMN2 3947/4885 |
| US-12312356-B2 | Anthelmintic heterocyclic compounds | AADAC, HNMT, HRH4 | NPC1 1209/4885RAB9A 1017/4885SMN1; SMN2 3947/4885 |
| US-20210380591-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | AADAC, HNMT, HRH4 | NPC1 1209/4885RAB9A 1017/4885SMN1; SMN2 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.