SCHEMBL24075489

SCHEMBL24075489

CC1(C)C=C(C#N)C=CC(C#N)=C1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
TSHR P16473 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
CYP2A6 P11509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28181339 0.66 CA1 (0.30)
SCHEMBL27481364 0.66
SCHEMBL17573814 0.66 CA1 (0.30)
SCHEMBL11790014 0.61
SCHEMBL819145 0.51 TSHR (0.59) MEN1TSHRKMT2AALDH1A1CYP2A6
SCHEMBL31050110 0.49 CYP1A2 (0.46) MEN1TSHRKMT2AALDH1A1CYP2A6
SCHEMBL119203 0.49 TSHR (0.50) MEN1TSHRKMT2AALDH1A1CYP2A6
Acetonitrile SCHEMBL25293727 0.48 ALDH1A1 (0.50) TSHRKMT2AALDH1A1CYP2A6
SCHEMBL16189170 0.48
SCHEMBL4632645 0.48 ALDH1A1 (0.44) MEN1TSHRKMT2AALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021239568-A1 PREPARATION OF SUBSTITUTED 4-(N'-HYDROXYCARBAMIMIDOYL)BENZOIC ACIDS BASF SE (DE) 2021-12-02 WO disclosed