Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24075668 | 1.00 | SMN1; SMN2 (0.33) | SMN1; SMN2PARP1HTR5AHSP90AA1MAOA | |
| SCHEMBL24074882 | 0.76 | AHR (0.33) | — | |
| SCHEMBL24075517 | 0.76 | PBRM1 (0.36) | TP53MEN1KMT2A | |
| SCHEMBL24075508 | 0.76 | MAPT (0.38) | MAOAMAOBTP53 | |
| SCHEMBL24075666 | 0.73 | GSTP1 (0.37) | MEN1KMT2A | |
| SCHEMBL24074878 | 0.73 | FFAR4 (0.38) | — | |
| SCHEMBL24074877 | 0.73 | HTR1A (0.34) | SMN1; SMN2HTT | |
| SCHEMBL24074881 | 0.71 | HTR2B (0.36) | BRD4CREBBP | |
| SCHEMBL24075744 | 0.70 | ABL1 (0.39) | SMN1; SMN2MAOATP53MEN1KMT2A | |
| SCHEMBL24075505 | 0.70 | CA12 (0.39) | SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021238588-A1 | OXATHIAZINE COMPOUND AND USE THEREOF | 四川大学华西医院 | 2021-12-02 | — | — | WO | disclosed |