Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 4/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24074878 | 0.91 | FFAR4 (0.38) | — | |
| SCHEMBL24075666 | 0.83 | GSTP1 (0.37) | MAPTTDP1AKR1B1LTA4H | |
| SCHEMBL24075827 | 0.77 | GSTP1 (0.39) | LTA4H | |
| SCHEMBL24075830 | 0.76 | SMN1; SMN2 (0.33) | MAOBMAOATP53 | |
| SCHEMBL24075668 | 0.76 | SMN1; SMN2 (0.33) | MAOBMAOATP53 | |
| SCHEMBL24075744 | 0.76 | ABL1 (0.39) | MAPTTDP1MAOATP53 | |
| SCHEMBL24075509 | 0.74 | MAPT (0.39) | MAPTTDP1L3MBTL1MAOBMAOA | |
| SCHEMBL24074882 | 0.74 | AHR (0.33) | — | |
| SCHEMBL24068988 | 0.69 | L3MBTL1 (0.39) | MAPTTDP1L3MBTL1MAOBMAOA | |
| SCHEMBL24075517 | 0.65 | PBRM1 (0.36) | MAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021238588-A1 | OXATHIAZINE COMPOUND AND USE THEREOF | 四川大学华西医院 | 2021-12-02 | — | — | WO | disclosed |