Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8283549 | 1.00 | LTA4H (0.37) | LTA4HMEN1KMT2ACHRNB4CHRNA3 | |
| SCHEMBL24075799 | 1.00 | LTA4H (0.37) | LTA4HMEN1KMT2ACHRNB4CHRNA3 | |
| SCHEMBL12891532 | 0.81 | MAP3K14 (0.38) | LTA4HMEN1KMT2ACHRNB4CHRNA3 | |
| SCHEMBL12891533 | 0.81 | MAP3K14 (0.38) | LTA4HMEN1KMT2ACHRNB4CHRNA3 | |
| SCHEMBL10297720 | 0.81 | MAP3K14 (0.38) | LTA4HMEN1KMT2ACHRNB4CHRNA3 | |
| SCHEMBL14661123 | 0.77 | LTA4H (0.40) | LTA4HMEN1KMT2ACHRNB4CHRNA3 | |
| SCHEMBL19852041 | 0.77 | P2RX7 (0.39) | LTA4HMEN1KMT2ACYP19A1NISCH | |
| SCHEMBL25442537 | 0.77 | MEN1 (0.37) | MEN1KMT2ACYP19A1 | |
| SCHEMBL25442536 | 0.77 | MEN1 (0.37) | MEN1KMT2ACYP19A1 | |
| SCHEMBL25442491 | 0.77 | MEN1 (0.37) | MEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242581-A1 | ANTHELMINTIC HETEROCYCLIC COMPOUNDS | Boehringer Ingelheim Animal Health USA Inc. (US) | 2021-12-02 | — | — | WO | disclosed |