Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498780 | 0.91 | CALM1 (0.55) | CALM1ALDH1A1LOXL2MAOAMAOB | |
| SCHEMBL10703356 | 0.85 | MAOB (0.42) | CALM1ALDH1A1MAOAMAOBMEN1 | |
| SCHEMBL5426526 | 0.83 | IDH1 (0.45) | CALM1ALDH1A1MEN1LMNAGAA | |
| SCHEMBL1704793 | 0.81 | CALM1 (0.44) | CALM1HTR2A | |
| SCHEMBL11406170 | 0.81 | CALM1 (0.44) | CALM1ALDH1A1LOXL2MAOAMAOB | |
| SCHEMBL28852466 | 0.80 | ALDH1A1 (0.42) | CALM1ALDH1A1MAOBMEN1LMNA | |
| SCHEMBL29974970 | 0.80 | ALDH1A1 (0.42) | CALM1ALDH1A1MAOBMEN1LMNA | |
| SCHEMBL6557214 | 0.79 | CALM1 (0.52) | CALM1ALDH1A1LOXL2MAOAMAOB | |
| SCHEMBL16054535 | 0.79 | CALM1 (0.42) | CALM1ALDH1A1LOXL2MAOAMAOB | |
| Bromide SCHEMBL5088657 | 0.79 | HTR2A (0.42) | CALM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110212122-A1 | Nerve Growth Factor Conjugates and Uses Thereof | CYTOS BIOTECHNOLOGY AG (CH) | 2011-09-01 | — | — | US | disclosed |
| CN-101951943-A | NGF conjugates and uses thereof | CYTOS BIOTECHNOLOGY AG | 2011-01-19 | — | — | CN | disclosed |
| EP-2231179-A2 | NGF CONJUGATES AND USES THEREOF | Cytos Biotechnology AG (CH) | 2010-09-29 | — | — | EP | disclosed |
| WO-2009080823-A2 | NERVE GROWTH FACTOR CONJUGATES AND USES THEREOF | CYTOS BIOTECHNOLOGY AG (CH) | 2009-07-02 | — | — | WO | disclosed |