Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
| ▸ | MAP2K4 | P45985 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | MAPK6 | Q16659 | 3/20 | 0.40 |
| ▸ | MAPKAPK3 | Q16644 | 2/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168572 | 1.00 | MEN1 (0.47) | MEN1KMT2AMAPTPARP1AURKB | |
| SCHEMBL25747164 | 0.81 | MAPT (0.42) | MAPTPARP1AURKBSMN1; SMN2PRMT5 | |
| SCHEMBL25746163 | 0.80 | CHEK1 (0.39) | KMT2AMAPTPARP1AURKBPRMT5 | |
| SCHEMBL24076277 | 0.78 | DAO (0.38) | KMT2AMAPTPARP1PRMT5WDR77 | |
| SCHEMBL24077389 | 0.78 | ATM (0.44) | MEN1KMT2AMAPTPARP1AURKB | |
| SCHEMBL24076861 | 0.77 | PDE2A (0.44) | MEN1KMT2AMAPTPARP1AURKB | |
| SCHEMBL24076862 | 0.77 | MAPT (0.47) | MAPTPARP1AURKBSMN1; SMN2PRMT5 | |
| SCHEMBL24076899 | 0.77 | MAPT (0.53) | MAPTPARP1SMN1; SMN2PRMT5WDR77 | |
| SCHEMBL29426569 | 0.77 | MAPT (0.44) | MAPTPARP1AURKBSMN1; SMN2PRMT5 | |
| SCHEMBL24076896 | 0.77 | MAPT (0.44) | MAPTPARP1AURKBSMN1; SMN2PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| CN-115667225-A | Compound (I) | 詹森药业有限公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2021239885-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | NLRP3, NLRP1, IL1B | MEN1 1965/4885KMT2A 4649/4885MAPT 1004/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.