Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 8/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24076326 | 0.93 | NLRP3 (0.58) | NLRP3POLBCHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL26732419 | 0.93 | NLRP3 (0.58) | NLRP3POLBCHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL26732418 | 0.93 | NLRP3 (0.58) | NLRP3POLBCHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL24077166 | 0.91 | NLRP3 (0.51) | NLRP3POLBCHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL24076405 | 0.90 | NLRP3 (0.49) | NLRP3POLBCHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL26732421 | 0.90 | NLRP3 (0.54) | NLRP3POLBCHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL26731971 | 0.90 | NLRP3 (0.54) | NLRP3POLBCHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL26630526 | 0.90 | NLRP3 (0.54) | NLRP3POLBCHRNA7ALDH1A1SMN1; SMN2 | |
| SCHEMBL31513493 | 0.87 | NLRP3 (0.49) | NLRP3CHRNA7ALDH1A1SMN1; SMN2THRB | |
| SCHEMBL26049497 | 0.87 | NLRP3 (0.49) | NLRP3CHRNA7ALDH1A1SMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| WO-2021239885-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | NLRP3, NLRP1, IL1B | NLRP3 1/4885POLB 3231/4885CHRNA7 4582/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.