SCHEMBL240771

SCHEMBL240771

CCc1ccc(O)c(F)c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.64
SHBG P04278 1/20 0.47
BACE1 P56817 1/20 0.46
CYP17A1 P05093 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP19A1 P11511 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
POLB P06746 1/20 0.44
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
DBH P09172 1/20 0.44
MGLL Q99685 1/20 0.42
CNR1 P21554 1/20 0.42
CNR2 P34972 1/20 0.42
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23250680 0.84 TRPA1 (0.55) TRPA1BACE1POLBKDM4EALDH1A1
SCHEMBL1524010 0.83 CNR1 (0.64) SHBGBACE1CYP3A4CNR1CNR2
SCHEMBL241420 0.82 TRPA1 (0.64) TRPA1BACE1
SCHEMBL30058625 0.81 CA1 (0.61) SHBGCYP17A1CYP3A4CYP19A1CYP11B1
SCHEMBL1338001 0.81 KDM4E (0.52) BACE1CYP17A1CYP3A4CYP19A1CYP11B1
SCHEMBL545298 0.81 CA1 (0.61) SHBGCYP17A1CYP3A4CYP19A1CYP11B1
SCHEMBL8443334 0.79 NPC1 (0.55) SHBGBACE1CYP3A4ESR1CNR1
SCHEMBL1390780 0.79 CYP17A1 (0.46) SHBGBACE1CYP17A1CYP3A4CYP19A1
SCHEMBL30683156 0.79 CYP17A1 (0.46) SHBGBACE1CYP17A1CYP3A4CYP19A1
SCHEMBL6890833 0.79 CYP17A1 (0.46) SHBGCYP17A1CYP3A4CYP19A1CYP11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113396137-A Method for producing 1,1, 1-trifluoro-2, 2-bisarylethane, and 1,1, 1-trifluoro-2, 2-bisarylethane 中央硝子株式会社 2021-09-14 CN claimed
CN-101624442-A Polycarbonate resin and electrophotographic photoreceptor using the same IDEMITSU KOSAN CO 2010-01-13 CN claimed
CN-1894818-A Fuel for fuel cell, fuel cell and use thereof KURITA WATER IND LTD (JP) 2007-01-10 CN claimed
CN-1659174-A Hydrogen storage method, hydrogen clathrate and process for producing the same KURITA WATER IND LTD (JP) 2005-08-24 CN claimed
US-20240228770-A1 RESIN PARTICLES, METHOD FOR PRODUCING RESIN PARTICLES, TONER, DEVELOPER, TONER STORAGE, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2024-07-11 US disclosed
CN-115190894-B Curable resin, curable resin composition, cured product, electronic device, laminate material, electronic component sealing material, and method for producing curable resin 中央硝子株式会社 2024-06-21 CN disclosed
CN-116736653-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2023-09-12 CN disclosed
WO-2023091578-A1 LIQUID MOLD COMPOUNDS, REACTION PRODUCTS OF WHICH BECOME PLATABLE UPON EXPOSURE TO LASER ENERGY HENKEL AG & CO. KGAA (DE) 2023-05-25 WO disclosed
US-20230038124-A1 NOVEL SUBSTITUTED CONDENSED RING COMPOUND Sumitomo Pharma Co., Ltd. (JP) 2023-02-09 US disclosed
WO-2022253101-A1 PYRIDAZINONE COMPOUND AS PARP7 INHIBITOR 上海优理惠生医药有限公司 2022-12-08 WO disclosed
WO-2022246086-A1 ANTIBODY DRUG CONJUGATES USING MATES TECHNOLOGY FOR DELIVERING CYTOTOXIC AGENTS BIOHAVEN THERAPEUTICS LTD. (US) 2022-11-24 WO disclosed
CN-115190894-A Curable resin, curable resin composition, cured product, electronic device, laminate material, electronic component sealing material, and method for producing curable resin 中央硝子株式会社 2022-10-14 CN disclosed
EP-1361241-A1 Process for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-11-12 EP disclosed
WO-2003068235-A1 NICOTINAMIDE DERIVATIVES USEFUL AS PDE4 INHIBITORS PFIZER LIMITED (GB) 2003-08-21 WO disclosed
CN-1364176-A Processes for producing raw polycarbonate resin material and producing polycarbonate resin IDEMITSU PETROCHEMICAL CO (JP) 2002-08-14 CN disclosed
EP-0709358-B1 NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIFOULING AGENT NIPPON SODA CO (JP) 1999-10-13 EP disclosed
EP-0816349-A1 NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND COATING COMPOSITION CONTAINING SAID NOVEL CLATHRATE COMPOUND ROHM AND HAAS COMPANY (US) 1998-01-07 EP disclosed
EP-0709358-A1 NOVEL CLATHRATE COMPOUND, PROCESS FOR PRODUCING THE SAME, AND ANTIFOULING AGENT NIPPON SODA CO., LTD. (JP) 1996-05-01 EP disclosed
US-5389444-A Polycarbonate containing styrylamine repeating unit and emitter, and hole injecting material IDEMITSU KOSAN CO., LTD. (JP) 1995-02-14 US disclosed
EP-0557534-A1 ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-09-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230038124-A1 NOVEL SUBSTITUTED CONDENSED RING COMPOUND CYP51A1, HDAC11, MMP9 TRPA1 3670/4885SHBG 3382/4885BACE1 10/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.