Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 9/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.35 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25749237 | 0.91 | NLRP3 (0.49) | NLRP3POLBCHRNA7TP53HTT | |
| SCHEMBL24077073 | 0.90 | NLRP3 (0.52) | NLRP3NPSR1POLBCHRNA7TP53 | |
| SCHEMBL24077047 | 0.85 | NLRP3 (0.48) | NLRP3NPSR1POLBCHRNA7NR5A1 | |
| SCHEMBL24077051 | 0.84 | NLRP3 (0.53) | NLRP3POLBCHRNA7TP53HTT | |
| SCHEMBL26732419 | 0.84 | NLRP3 (0.58) | NLRP3POLBCHRNA7THRB | |
| SCHEMBL26732418 | 0.84 | NLRP3 (0.58) | NLRP3POLBCHRNA7THRB | |
| SCHEMBL24076326 | 0.84 | NLRP3 (0.58) | NLRP3POLBCHRNA7THRB | |
| SCHEMBL24077114 | 0.84 | NLRP3 (0.51) | NLRP3POLBCHRNA7 | |
| SCHEMBL24077072 | 0.83 | NLRP3 (0.51) | NLRP3POLBCHRNA7TP53THRB | |
| SCHEMBL24077055 | 0.82 | NLRP3 (0.52) | NLRP3POLBCHRNA7TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| WO-2021239885-A1 | COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-12-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202989-A1 | COMPOUNDS | NLRP3, NLRP1, IL1B | NLRP3 1/4885NPSR1 295/4885POLB 3231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.