SCHEMBL2407776

SCHEMBL2407776

C=C(C)C(=O)OCCNC(=O)OCCOCCOCCOCCOC(=O)C(=C)C

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.58
ACHE P22303 9/20 0.46
TSHR P16473 3/20 0.43
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
ALDH1A1 P00352 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13872027 1.00 THRB (0.58) THRBACHETSHRLMNASMN1; SMN2
SCHEMBL22035555 0.98 THRB (0.59) THRBACHETSHRLMNASMN1; SMN2
SCHEMBL27441392 0.95 THRB (0.53) THRBACHETSHRLMNASMN1; SMN2
SCHEMBL13872030 0.95 THRB (0.53) THRBACHETSHRALDH1A1L3MBTL1
SCHEMBL2403793 0.95 THRB (0.53) THRBACHETSHRALDH1A1L3MBTL1
SCHEMBL29700318 0.94 THRB (0.56) THRBACHETSHRLMNASMN1; SMN2
SCHEMBL21404625 0.94 THRB (0.51) THRBACHETSHRLMNASMN1; SMN2
SCHEMBL3821239 0.94 THRB (0.51) THRBACHETSHRLMNASMN1; SMN2
SCHEMBL15128212 0.94 THRB (0.51) THRBACHETSHRLMNASMN1; SMN2
SCHEMBL14904497 0.94 THRB (0.70) THRBACHETSHRLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020237363-A1 COMPOSITE PARTICLES COMPRISING A HYDROPHOBIC DYE AND AN AMPHIPHILIC BLOCK COPOLYMER AND USE THEREOF IN OPTICAL APPLICATIONS COLOURSMITH LABS INC. (CA) 2020-12-03 WO disclosed
EP-1789821-B1 SILICONE HYDROGEL CONTACT LENSES COOPERVISION INT HOLDING CO LP (BB) 2019-04-10 EP disclosed
US-9322958-B2 Silicone hydrogel contact lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2016-04-26 US disclosed
US-20150219795-A9 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL LIMITED (GB) 2015-08-06 US disclosed
US-20140200286-A1 Silicone Hydrogel Contact Lenses COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2014-07-17 US disclosed
US-8637621-B2 Long-wearable soft contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2014-01-28 US disclosed
US-8614261-B2 Silicone hydrogel contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY LP (BB) 2013-12-24 US disclosed
EP-1243960-B2 SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD COOPERVISION INT HOLDING CO LP (BB) 2013-10-16 EP disclosed
US-8367746-B2 Silicone hydrogel contact lens COOPERVISION INTERNATIONAL HOLDING COMPANY (BB) 2013-02-05 US disclosed
US-20120252925-A1 Silicone Hydrogel Contact Lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-10-04 US disclosed
US-20110211158-A1 Long-Wearable Soft Contact Lens COOPERVISION INTERNATIONAL LIMITED (GB) 2011-09-01 US disclosed
EP-1789821-A2 SILICONE HYDROGEL CONTACT LENSES ASAHIKASEI AIME CO., Ltd. (JP) 2007-05-30 EP disclosed
US-20070066706-A1 Silicone hydrogel contact lens COOPERVISION, INC. (US) 2007-03-22 US disclosed
US-20060211789-A1 Long-wearable soft contact lens ASAHIKASEI AIME CO., LTD. (JP) 2006-09-21 US disclosed
US-20060063852-A1 Silicone hydrogel contact lens ASAHIKASEI AIME CO. LTD. (JP) 2006-03-23 US disclosed
WO-2006026474-A2 SILICONE HYDROGEL CONTACT LENSES ASAHIKASEI AIME CO. LTD. (JP) 2006-03-09 WO disclosed
US-20040192872-A1 Long-wearable soft contact lens ASAHIKASEI AIME CO., LTD (JP) 2004-09-30 US disclosed
EP-1243960-A1 SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD ASAHIKASEI AIME CO., Ltd. (JP) 2002-09-25 EP disclosed
US-20020016383-A1 Long wearable soft contact lens COOPERVISION INTERNATIONAL LIMITED (GB) 2002-02-07 US disclosed