Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 12/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3821239 | 1.00 | THRB (0.51) | THRBACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL21404666 | 0.98 | THRB (0.53) | THRBACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL21404715 | 0.98 | THRB (0.53) | THRBACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL2407776 | 0.94 | THRB (0.58) | THRBACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL13872027 | 0.94 | THRB (0.58) | THRBACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL22035555 | 0.92 | THRB (0.59) | THRBACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL10216111 | 0.91 | ACHE (0.54) | THRBACHETSHRCHRNB2CHRNB4 | |
| SCHEMBL27441392 | 0.89 | THRB (0.53) | THRBACHETSHRLMNASMN1; SMN2 | |
| SCHEMBL13872030 | 0.89 | THRB (0.53) | THRBACHETSHR | |
| SCHEMBL2403793 | 0.89 | THRB (0.53) | THRBACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12152045-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2024-11-26 | — | — | US | disclosed |
| CN-110317226-B | Silane coupling compounds and curable dental compositions containing the same | 株式会社松风 | 2023-12-19 | — | — | CN | disclosed |
| US-20210122770-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2021-04-29 | — | — | US | disclosed |
| US-10975229-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | KABUSHIKI KAISHA SHOFU (JP) | 2021-04-13 | — | — | US | disclosed |
| US-20190300552-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | KABUSHIKI KAISHA SHOFU (JP) | 2019-10-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122770-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | SMCHD1, CAD, EPM2A | THRB 3383/4885ACHE 3391/4885TSHR 2902/4885 |
| US-10975229-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | SMCHD1, CAD, EPM2A | THRB 3383/4885ACHE 3391/4885TSHR 2902/4885 |
| US-12152045-B2 | Silane coupling compounds and medical and/or dental curable compositions comprising the same | SMCHD1, CAD, EPM2A | THRB 3383/4885ACHE 3391/4885TSHR 2902/4885 |
| US-20190300552-A1 | SILANE COUPLING COMPOUNDS AND MEDICAL AND/OR DENTAL CURABLE COMPOSITIONS COMPRISING THE SAME | SMCHD1, CAD, EPM2A | THRB 3383/4885ACHE 3391/4885TSHR 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.