Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28470543 | 0.79 | MAPK1 (0.40) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL28626993 | 0.79 | MAPK1 (0.40) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL19909627 | 0.79 | MAPK1 (0.43) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL19148226 | 0.74 | POLB (0.43) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL21357724 | 0.72 | MAPK1 (0.38) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL28468166 | 0.72 | MAPK1 (0.38) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL21363297 | 0.70 | ALDH1A1 (0.37) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL13772455 | 0.69 | HSD17B10 (0.60) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL21818744 | 0.69 | MAPK1 (0.40) | MAPK1ALDH1A1POLBAPEX1RECQL | |
| SCHEMBL29876882 | 0.69 | MEN1 (0.40) | MAPK1ALDH1A1POLBAPEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192886-B2 | S1P1 agonist and application thereof | MEDSHINE DISCOVERY INC. (CN) | 2021-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192886-B2 | S1P1 agonist and application thereof | S1PR1, S1PR2, S1PR3 | MAPK1 756/4885ALDH1A1 2418/4885POLB 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.