Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24079283 | 0.79 | MAPK1 (0.40) | MAPK1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL28470543 | 0.79 | MAPK1 (0.40) | MAPK1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL19909627 | 0.79 | MAPK1 (0.43) | MAPK1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL23645338 | 0.77 | MAPT (0.53) | MAPK1ALDH1A1POLBKMT2AHPGD | |
| SCHEMBL2713917 | 0.75 | POLB (0.41) | MAPK1ALDH1A1POLBMEN1KMT2A | |
| SCHEMBL19148226 | 0.74 | POLB (0.43) | MAPK1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL28468166 | 0.72 | MAPK1 (0.38) | MAPK1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL21357724 | 0.72 | MAPK1 (0.38) | MAPK1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL21363297 | 0.70 | ALDH1A1 (0.37) | MAPK1ALDH1A1POLBTDP1L3MBTL1 | |
| SCHEMBL13772455 | 0.69 | HSD17B10 (0.60) | MAPK1ALDH1A1POLBTDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112689636-A | Novel heteroatom aromatic amide derivative and drug containing the same | 科研制药株式会社 | 2021-04-20 | — | — | CN | disclosed |