SCHEMBL24080171

SCHEMBL24080171

Nc1ccc(CCc2cc(N)cc(N)c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
GFER P55789 1/20 0.74
CYP19A1 P11511 5/20 0.64
MAOB P27338 6/20 0.61
MAOA P21397 4/20 0.61
ALDH1A1 P00352 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
LOXL2 Q9Y4K0 1/20 0.48
CHKA P35790 1/20 0.45
RECQL P46063 1/20 0.45
GRK6 P43250 1/20 0.43
MEN1 O00255 1/20 0.42
MAPT P10636 1/20 0.42
KMT2A Q03164 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3482833 0.86 GFER (1.00) GFERCYP19A1MAOBMAOAALDH1A1
SCHEMBL8164156 0.86 GFER (1.00) GFERCYP19A1MAOBMAOAALDH1A1
SCHEMBL187043 0.86 GFER (1.00) GFERCYP19A1MAOBMAOAALDH1A1
SCHEMBL720452 0.83 LTA4H (0.64) GFERCYP19A1MAOBMAOAALDH1A1
Hydrochloric Acid SCHEMBL8653872 0.83 GFER (0.93) GFERCYP19A1MAOBMAOAALDH1A1
SCHEMBL19105196 0.82 MAOB (0.71) GFERCYP19A1MAOBMAOAALDH1A1
SCHEMBL12110688 0.78 GFER (0.82) GFERCYP19A1MAOBMAOAALDH1A1
SCHEMBL6362605 0.78 CYP3A4 (0.82) GFERCYP19A1MAOBMAOAALDH1A1
SCHEMBL18469205 0.78 TAAR1 (0.43) GFERALDH1A1TDP1LOXL2RECQL
SCHEMBL12110804 0.76 GFER (0.78) GFERCYP19A1MAOBMAOAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667737-B1 Thermosetting polyimides derived from resveratrol THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-06-06 US disclosed
US-11667737-B1 Thermosetting polyimides derived from resveratrol THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2023-06-06 US disclosed
US-11192967-B1 Thermosetting polyimides derived from resveratrol THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2021-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667737-B1 Thermosetting polyimides derived from resveratrol RICTOR, MAP1LC3C, DEPTOR GFER 1859/4885CYP19A1 2828/4885MAOB 3270/4885
US-11192967-B1 Thermosetting polyimides derived from resveratrol RICTOR, MAP1LC3C, DEPTOR GFER 1859/4885CYP19A1 2828/4885MAOB 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.