Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 7/20 | 0.44 |
| ▸ | BCL2 | P10415 | 5/20 | 0.44 |
| ▸ | TYMS | P04818 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23430836 | 0.79 | MCL1 (0.56) | MCL1BCL2TYMSPOLBKMT2A | |
| SCHEMBL30970627 | 0.74 | HTT (0.41) | TYMSPOLBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL13753885 | 0.73 | MCL1 (0.51) | MCL1BCL2TYMSPOLBKMT2A | |
| SCHEMBL30930083 | 0.72 | HTT (0.50) | POLBHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL12774689 | 0.72 | HTT (0.50) | POLBHTTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL16291732 | 0.72 | TYMS (0.53) | MCL1BCL2TYMSPOLBKMT2A | |
| SCHEMBL24598723 | 0.72 | HTT (0.47) | MCL1BCL2POLBKMT2AHTT | |
| SCHEMBL1198049 | 0.70 | ADORA2A (0.50) | MCL1BCL2POLBKMT2AHTT | |
| SCHEMBL15177181 | 0.70 | MCL1 (0.58) | MCL1BCL2POLBKMT2AHTT | |
| SCHEMBL28028227 | 0.70 | MCL1 (0.44) | MCL1BCL2POLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11193020-B2 | Polyarylene ether sulfone comprising naphthalic acid anhydride endgroups | BASF SE (DE) | 2021-12-07 | — | — | US | disclosed |