Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 8/20 | 0.56 |
| ▸ | BCL2 | P10415 | 6/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TYMS | P04818 | 6/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15177181 | 0.88 | MCL1 (0.58) | MCL1BCL2KMT2APOLBBCL2L1 | |
| SCHEMBL11714791 | 0.82 | MCL1 (0.53) | MCL1BCL2KMT2AMEN1POLB | |
| SCHEMBL18071160 | 0.79 | BCL2 (0.56) | MCL1BCL2KMT2AMEN1POLB | |
| SCHEMBL13753885 | 0.79 | MCL1 (0.51) | MCL1BCL2KMT2AMEN1POLB | |
| SCHEMBL24080349 | 0.79 | MCL1 (0.44) | MCL1BCL2KMT2AMEN1POLB | |
| SCHEMBL16291732 | 0.78 | TYMS (0.53) | MCL1BCL2KMT2AMEN1POLB | |
| SCHEMBL30761754 | 0.78 | KMT2A (0.76) | MCL1KMT2AMEN1POLBTYMS | |
| SCHEMBL6548245 | 0.78 | KMT2A (0.76) | MCL1KMT2AMEN1POLBTYMS | |
| SCHEMBL14303997 | 0.76 | KMT2A (0.49) | MCL1BCL2KMT2AMEN1POLB | |
| SCHEMBL17726919 | 0.75 | TYMS (0.49) | KMT2AMEN1POLBTYMSPRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3577164-B1 | POLYARYLENE ETHER SULFONE COMPRISING NAPHTHALIC ACID ANHYDRIDE ENDGROUPS | BASF SE (DE) | 2021-06-02 | — | — | EP | disclosed |