Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.39 |
| ▸ | CASP1 | P29466 | 5/20 | 0.39 |
| ▸ | CASP7 | P55210 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.39 |
| ▸ | ESR1 | P03372 | 4/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408379 | 0.99 | RPS6KA3 (0.48) | RPS6KA3PIM1FGFR1ALDH1A1CYP1A2 | |
| SCHEMBL2407473 | 0.87 | ALDH1A1 (0.54) | RPS6KA3ALDH1A1CYP1A2HSD17B10CASP1 | |
| SCHEMBL2411816 | 0.87 | RPS6KA3 (0.55) | RPS6KA3ALDH1A1CYP1A2HSD17B10CASP1 | |
| SCHEMBL22411573 | 0.85 | RPS6KA3 (0.44) | RPS6KA3FGFR1ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2406067 | 0.84 | JAK3 (0.45) | RPS6KA3FGFR1ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2410911 | 0.84 | CFTR (0.45) | RPS6KA3FGFR1ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2409783 | 0.83 | RPS6KA3 (0.43) | RPS6KA3ALDH1A1CYP1A2HSD17B10CASP1 | |
| SCHEMBL2409354 | 0.83 | ESR1 (0.44) | RPS6KA3ALDH1A1CYP1A2HSD17B10CASP1 | |
| SCHEMBL2407291 | 0.83 | CFTR (0.46) | RPS6KA3FGFR1ALDH1A1CYP1A2HSD17B10 | |
| SCHEMBL2407675 | 0.82 | ESR1 (0.45) | RPS6KA3ALDH1A1CYP1A2HSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | claimed |
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | disclosed |
| WO-2011106168-A1 | PURINE COMPOUNDS FOR TREATING AUTOIMMUNE AND DEMYELINATING DISEASES | DCAM PHARMA INC (US) | 2011-09-01 | — | — | WO | disclosed |