Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MPI | P34949 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | METAP2 | P50579 | 1/20 | 0.58 |
| ▸ | METAP1 | P53582 | 1/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.58 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22705016 | 0.84 | IDO1 (0.64) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| SCHEMBL15217626 | 0.84 | IDO1 (0.69) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| SCHEMBL28942142 | 0.84 | IDO1 (0.64) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| SCHEMBL14130573 | 0.84 | IDO1 (0.64) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| SCHEMBL1920452 | 0.80 | KDM4E (0.70) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| SCHEMBL12599076 | 0.80 | IDO1 (1.00) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| SCHEMBL12599074 | 0.80 | IDO1 (1.00) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| SCHEMBL7032474 | 0.78 | IDO1 (0.61) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| Methane SCHEMBL27551425 | 0.78 | KDM4E (0.68) | IDO1KDM4EL3MBTL1HSP90AA1HTT | |
| SCHEMBL27816447 | 0.78 | KDM4E (0.68) | IDO1KDM4EL3MBTL1HSP90AA1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3007709-B1 | LIPID-BASED PLATINUM COMPOUNDS AND NANOPARTICLES | AKAMARA THERAPEUTICS INC (US) | 2021-12-08 | — | — | EP | disclosed |