Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 7/20 | 0.47 |
| ▸ | NQO2 | P16083 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22309754 | 0.86 | MET (0.58) | METNQO2ACHEGPR119KDM4E | |
| SCHEMBL22309813 | 0.82 | MET (0.42) | METNQO2ACHECARM1PRMT6 | |
| SCHEMBL13180993 | 0.79 | MET (0.66) | METNQO2 | |
| SCHEMBL22310321 | 0.79 | EP300 (0.53) | METNQO2 | |
| SCHEMBL2454544 | 0.78 | MET (0.82) | METNQO2 | |
| SCHEMBL12547598 | 0.77 | MET (0.57) | METNQO2ACHE | |
| SCHEMBL1296276 | 0.77 | MET (0.57) | METNQO2ACHE | |
| SCHEMBL31495087 | 0.77 | MET (0.57) | METNQO2ACHE | |
| SCHEMBL13449240 | 0.73 | MET (0.53) | METNQO2ACHEALDH1A1 | |
| SCHEMBL31495102 | 0.73 | MET (0.53) | METNQO2ACHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3919492-A1 | PYRIMIDINYL GROUP-CONTAINING TRICYCLIC COMPOUND SERVING AS C-MET INHIBITOR | Medshine Discovery Inc. (CN) | 2021-12-08 | — | — | EP | disclosed |