Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 9/20 | 1.00 |
| ▸ | TRPC3 | Q13507 | 4/20 | 1.00 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 1.00 |
| ▸ | SLC9A3 | P48764 | 11/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2370271 | 1.00 | TRPC6 (1.00) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL31337541 | 0.99 | TRPC6 (0.98) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2410193 | 0.94 | TRPC6 (0.89) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12363384 | 0.94 | TRPC6 (0.89) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2414847 | 0.94 | TRPC6 (0.89) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL14955681 | 0.93 | TRPC6 (0.86) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2411411 | 0.93 | TRPC6 (0.86) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2414190 | 0.93 | TRPC6 (0.86) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12363341 | 0.92 | TRPC6 (0.85) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12363365 | 0.92 | TRPC6 (0.85) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-05-23 | — | — | US | claimed |
| EP-2542524-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-01-09 | — | — | EP | claimed |
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | claimed |
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-05-23 | — | — | US | disclosed |
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-05-23 | — | — | US | disclosed |
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-05-23 | — | — | US | disclosed |
| EP-2542524-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-01-09 | — | — | EP | disclosed |
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | ANXA2, ANXA3, ADM2 | TRPC6 3080/4885TRPC3 2333/4885TRPC7 3887/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.