Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC6 | Q9Y210 | 9/20 | 1.00 |
| ▸ | TRPC3 | Q13507 | 4/20 | 1.00 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 1.00 |
| ▸ | SLC9A3 | P48764 | 11/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2408180 | 1.00 | TRPC6 (1.00) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL31337541 | 0.99 | TRPC6 (0.98) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2410193 | 0.94 | TRPC6 (0.89) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12363384 | 0.94 | TRPC6 (0.89) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2414847 | 0.94 | TRPC6 (0.89) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL14955681 | 0.93 | TRPC6 (0.86) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2411411 | 0.93 | TRPC6 (0.86) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL2414190 | 0.93 | TRPC6 (0.86) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12363341 | 0.92 | TRPC6 (0.85) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 | |
| SCHEMBL12363365 | 0.92 | TRPC6 (0.85) | TRPC6TRPC3TRPC7SLC9A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4746923-A2 | DELIVERY SYSTEM COMPRISING LIPID OR POLYMERIC NANOPARTICLES COMPRISING THYROID HORMONES | FONDAZIONE RICCARDO TERZI E SILVIO ALBINI (IT) | 2026-05-27 | — | — | EP | claimed |
| EP-4103245-B1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | KLINIKUM DER TECHNISCHEN UNIV MUENCHEN TUM KLINIKUM (DE) | 2026-04-01 | — | — | EP | claimed |
| WO-2025017370-A2 | DELIVERY SYSTEM COMPRISING LIPID OR POLYMERIC NANOPARTICLES COMPRISING THYROID HORMONES | FONDAZIONE RICCARDO TERZI E SILVIO ALBINI (IT) | 2025-01-23 | — | — | WO | claimed |
| CN-114632160-B | Pharmaceutical composition for treating acute respiratory distress syndrome pulmonary edema and application thereof | 南京中医药大学 | 2023-10-13 | — | — | CN | claimed |
| CN-114632160-A | Pharmaceutical composition for treating acute respiratory distress syndrome pulmonary edema and application thereof | 南京中医药大学 | 2022-06-17 | — | — | CN | claimed |
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-05-23 | — | — | US | claimed |
| EP-2542524-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI (FR) | 2013-01-09 | — | — | EP | claimed |
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | claimed |
| EP-4746923-A2 | DELIVERY SYSTEM COMPRISING LIPID OR POLYMERIC NANOPARTICLES COMPRISING THYROID HORMONES | FONDAZIONE RICCARDO TERZI E SILVIO ALBINI (IT) | 2026-05-27 | — | — | EP | disclosed |
| CN-122028939-A | Thyroid hormone delivery system comprising lipid or polymer nanoparticles | 里卡尔多·泰尔齐与西尔维奥·阿尔比尼基金会 | 2026-05-12 | — | — | CN | disclosed |
| EP-4103245-B1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | KLINIKUM DER TECHNISCHEN UNIV MUENCHEN TUM KLINIKUM (DE) | 2026-04-01 | — | — | EP | disclosed |
| WO-2025017370-A2 | DELIVERY SYSTEM COMPRISING LIPID OR POLYMERIC NANOPARTICLES COMPRISING THYROID HORMONES | FONDAZIONE RICCARDO TERZI E SILVIO ALBINI (IT) | 2025-01-23 | — | — | WO | disclosed |
| CN-119235883-A | Pharmaceutical composition and application thereof | 苏中药业集团股份有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-112204017-B | Benzisoxazole compounds | 国立大学法人大阪大学 | 2024-08-20 | — | — | CN | disclosed |
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |
| EP-2368876-A1 | Derivatives of aminoindanes, their preparation and their application in therapeutics | SANOFI (FR) | 2011-09-28 | — | — | EP | disclosed |
| WO-2011107474-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2011-09-09 | — | — | WO | disclosed |
| WO-2011107474-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2011-09-09 | — | — | WO | disclosed |
| US-20110201590-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI-AVENTIS (FR) | 2011-08-18 | — | — | US | disclosed |
| US-20110201590-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI-AVENTIS (FR) | 2011-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131034-A1 | DERIVATIVES OF AMINOINDANES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS | ANXA2, ANXA3, ADM2 | TRPC6 3080/4885TRPC3 2333/4885TRPC7 3887/4885 |
| US-20110201590-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | CFTR, AADAT, PKD1 | TRPC6 2782/4885TRPC3 1207/4885TRPC7 2539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.