Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 6/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.41 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | POLG | P54098 | 1/20 | 0.41 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.40 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | PNP | P00491 | 1/20 | 0.39 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.39 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.39 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24081984 | 0.89 | P2RY1 (0.42) | P2RY1ENPP1P2RX1P2RX3P2RY11 | |
| SCHEMBL23760782 | 0.80 | P2RY1 (0.42) | P2RY1ENPP1P2RX1P2RX3P2RY11 | |
| SCHEMBL20058653 | 0.78 | P2RY1 (0.47) | P2RY1ENPP1P2RX1P2RX3P2RY11 | |
| SCHEMBL23761014 | 0.78 | P2RY1 (0.42) | P2RY1ENPP1P2RX1P2RX3P2RY11 | |
| SCHEMBL23760932 | 0.76 | P2RY1 (0.49) | P2RY1ENPP1P2RX1P2RX3P2RY11 | |
| SCHEMBL21257339 | 0.74 | P2RX3 (0.53) | P2RY1ENPP1P2RX1P2RX3P2RY11 | |
| SCHEMBL25720747 | 0.74 | P2RY1 (0.51) | P2RY1ENPP1P2RX1P2RX3P2RY11 | |
| SCHEMBL23760787 | 0.74 | P2RY1 (0.47) | P2RY1ENPP1P2RX1P2RX3P2RY11 | |
| SCHEMBL24081997 | 0.73 | P2RX3 (0.57) | P2RY1P2RX1P2RX3P2RY11P2RX4 | |
| SCHEMBL18503420 | 0.71 | P2RY1 (0.54) | P2RY1ENPP1P2RX1P2RX3P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512863-B1 | 2'-SUBSTITUTED-N6-SUBSTITUTED PURINE NUCLEOTIDES FOR RNA VIRUS TREATMENT | ATEA PHARMACEUTICALS INC (US) | 2021-12-08 | — | — | EP | disclosed |