Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 7/20 | 0.51 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.51 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.51 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.51 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.51 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.49 |
| ▸ | RNASEL | Q05823 | 2/20 | 0.48 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.48 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.47 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.47 |
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25712592 | 0.92 | P2RY1 (0.46) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL25720618 | 0.89 | P2RX1 (0.61) | P2RY1P2RX3P2RX1P2RX4P2RY11 | |
| SCHEMBL18503413 | 0.85 | P2RY1 (0.67) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL25723534 | 0.83 | RNASEL (0.47) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL20058653 | 0.80 | P2RY1 (0.47) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL13857854 | 0.78 | P2RY1 (0.79) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL625828 | 0.78 | P2RY1 (0.79) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL3502237 | 0.78 | P2RY1 (0.79) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL17211052 | 0.78 | P2RY1 (0.79) | P2RY1P2RX3P2RX1ENPP1P2RX4 | |
| SCHEMBL29471291 | 0.78 | P2RY1 (0.79) | P2RY1P2RX3P2RX1ENPP1P2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |