Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 10/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 6/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | CHRNA2 | Q15822 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8514392 | 1.00 | CHRNB2 (0.43) | CHRNB2CHRNA7CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL8512456 | 0.80 | ESR2 (0.40) | KMT2ATDP1 | |
| SCHEMBL8515623 | 0.80 | ESR2 (0.40) | KMT2ATDP1 | |
| SCHEMBL9047337 | 0.78 | CHRNB2 (0.46) | CHRNB2CHRNA7CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL9050188 | 0.78 | CHRNB2 (0.46) | CHRNB2CHRNA7CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL30847846 | 0.78 | CHRNB2 (0.53) | CHRNB2CHRNA7CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL1481609 | 0.78 | CHRNB2 (0.53) | CHRNB2CHRNA7CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL8795939 | 0.77 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL8795450 | 0.77 | CHRNB2 (0.41) | CHRNB2CHRNA7CHRNA3CHRNA4CHRNB4 | |
| SCHEMBL444141 | 0.77 | SRD5A1 (0.53) | ALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8017788-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017788-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2011-09-13 | — | — | US | disclosed |
| US-8017788-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2011-09-13 | — | — | US | disclosed |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-08 | — | — | US | disclosed |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | CORTEVA AGRISCIENCE LLC | 2010-07-08 | — | — | US | disclosed |
| US-7705156-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705156-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| US-7705156-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2010-04-27 | — | — | US | disclosed |
| CN-101535262-A | Heteroaryl (substituted) alkyl n-substituted sulfoximines as insecticides | DOW AGROSCIENCES LLC (US) | 2009-09-16 | — | — | CN | disclosed |
| EP-2094659-A1 | HETEROARYL (SUBSTITUTED) ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | Dow AgroSciences LLC (US) | 2009-09-02 | — | — | EP | disclosed |
| WO-2008057131-A1 | HETEROARYL (SUBSTITUTED) ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008057131-A1 | HETEROARYL (SUBSTITUTED) ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | STS, DDT, TST | CHRNB2 978/4885CHRNA7 1863/4885CHRNA3 1047/4885 |
| US-20100173962-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | STS, DDT, TST | CHRNB2 978/4885CHRNA7 1863/4885CHRNA3 1047/4885 |
| US-20100173950-A1 | HETEROARYL (SUBSTITUTED)ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | STS, DDT, TST | CHRNB2 978/4885CHRNA7 1863/4885CHRNA3 1047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.