Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 1/20 | 0.50 |
| ▸ | JAK1 | P23458 | 13/20 | 0.48 |
| ▸ | JAK3 | P52333 | 12/20 | 0.48 |
| ▸ | JAK2 | O60674 | 8/20 | 0.47 |
| ▸ | TYK2 | P29597 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18493479 | 0.74 | JAK3 (0.59) | CSF1RJAK1JAK3JAK2TYK2 | |
| SCHEMBL15086982 | 0.74 | JAK3 (0.62) | CSF1RJAK1JAK3JAK2TYK2 | |
| SCHEMBL8494081 | 0.72 | JAK1 (0.51) | CSF1RJAK1JAK3JAK2TYK2 | |
| SCHEMBL22651230 | 0.72 | ADORA2A (0.33) | — | |
| SCHEMBL18493472 | 0.72 | JAK1 (0.56) | CSF1RJAK1JAK3JAK2TYK2 | |
| SCHEMBL20343713 | 0.71 | JAK1 (0.59) | CSF1RJAK1JAK3JAK2TYK2 | |
| SCHEMBL22061391 | 0.71 | CSF1R (0.65) | CSF1RJAK1JAK3JAK2TYK2 | |
| SCHEMBL3534021 | 0.71 | CSF1R (0.53) | CSF1RJAK1JAK3JAK2TYK2 | |
| SCHEMBL3538291 | 0.70 | CSF1R (0.71) | CSF1RJAK1JAK3JAK2TYK2 | |
| SCHEMBL14342248 | 0.70 | JAK3 (0.54) | CSF1RJAK1JAK3JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2813228-B1 | AGENT FOR IMPROVEMENT OF SKIN BARRIER FUNCTION | JAPAN TOBACCO INC (JP) | 2021-12-08 | — | — | EP | disclosed |