Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 5/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | PI4KA | P42356 | 2/20 | 0.33 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.33 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19864857 | 0.77 | LIMK1 (0.33) | CDC7DBF4LIMK1L3MBTL1MEN1 | |
| SCHEMBL14048009 | 0.75 | — | — | |
| SCHEMBL24083604 | 0.72 | CSF1R (0.50) | — | |
| SCHEMBL26215426 | 0.67 | ALOX15 (0.32) | MEN1LMNAHTTKMT2A | |
| SCHEMBL19969968 | 0.67 | LIMK1 (0.33) | ADORA2AADORA1LIMK1L3MBTL1LMNA | |
| SCHEMBL17623163 | 0.66 | LIMK1 (0.38) | ADORA2AADORA1PI4KAPI4K2BPI4K2A | |
| SCHEMBL7519562 | 0.66 | — | — | |
| SCHEMBL23079428 | 0.65 | LMNA (0.33) | MEN1LMNAHTTKMT2A | |
| SCHEMBL22676747 | 0.65 | LIMK1 (0.34) | LIMK1L3MBTL1LMNA | |
| SCHEMBL10664748 | 0.63 | SMN1; SMN2 (0.42) | ADORA2AADORA1PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020227421-A1 | MODIFIED CYCLIC DINUCLEOSIDE COMPOUNDS AS STING MODULATORS | ALIGOS THERAPEUTICS, INC. (US) | 2020-11-12 | — | — | WO | disclosed |