Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.65 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24083694 | 0.90 | AR (0.56) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL26761198 | 0.90 | AR (0.56) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL24083794 | 0.89 | AR (0.55) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL24083793 | 0.89 | AR (0.63) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL24083678 | 0.88 | AR (0.54) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL12515785 | 0.86 | AR (0.88) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL6131219 | 0.86 | AR (0.88) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL24083954 | 0.85 | HTT (0.54) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL18120597 | 0.85 | KDM4E (0.71) | ARHTTHIF1AALDH1A1KDM4E | |
| SCHEMBL24377960 | 0.85 | AR (0.58) | ARHTTHIF1AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3245193-B1 | HETEROCYCLIC COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE | BRITISH COLUMBIA CANCER AGENCY BRANCH (CA) | 2021-12-08 | — | — | EP | disclosed |