Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24083864 | 0.85 | AR (0.67) | ARHTTHIF1AKDM4EMAPK1 | |
| SCHEMBL12515785 | 0.79 | AR (0.88) | ARHTTHIF1AKDM4EMAPK1 | |
| SCHEMBL6131219 | 0.79 | AR (0.88) | ARHTTHIF1AKDM4EMAPK1 | |
| SCHEMBL16281213 | 0.78 | AR (0.85) | ARHTTHIF1AKDM4EMAPK1 | |
| SCHEMBL24083793 | 0.77 | AR (0.63) | ARHTTHIF1AKDM4EMAPK1 | |
| SCHEMBL13189123 | 0.77 | AR (0.78) | ARHTTHIF1AKDM4EALDH1A1 | |
| SCHEMBL16232997 | 0.77 | AR (0.78) | ARHTTHIF1AKDM4EMAPK1 | |
| SCHEMBL13513162 | 0.77 | AR (0.78) | ARHTTHIF1AKDM4EMAPK1 | |
| SCHEMBL24083694 | 0.77 | AR (0.56) | ARHTTHIF1AKDM4EMAPK1 | |
| SCHEMBL26761198 | 0.77 | AR (0.56) | ARHTTHIF1AKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3988541-A1 | HETEROCYCLIC COMPOUNDS FOR CANCER IMAGING AND TREATMENT AND METHODS FOR THEIR USE | British Columbia Cancer Agency Branch (CA) | 2022-04-27 | — | — | EP | disclosed |