SCHEMBL240889

SCHEMBL240889

Oc1ccc(C#Cc2cc[c]cc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 8/20 0.56
CA3 P07451 3/20 0.50
CA14 Q9ULX7 3/20 0.50
CA12 O43570 2/20 0.50
CA2 P00918 2/20 0.50
CA9 Q16790 2/20 0.50
CA6 P23280 2/20 0.50
MMP3 P08254 2/20 0.44
ALOX15 P16050 3/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALDH1A1 P00352 2/20 0.40
CYP3A4 P08684 2/20 0.40
HIF1A Q16665 2/20 0.40
HSD17B10 Q99714 2/20 0.40
KDM4E B2RXH2 1/20 0.40
NPC1 O15118 1/20 0.40
GMNN O75496 1/20 0.40
CA1 P00915 1/20 0.40
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11883827 0.84 APP (0.44) APPMAPT
SCHEMBL673609 0.84 APP (0.74) APPCA3CA14CA12CA2
SCHEMBL14400750 0.84 APP (0.74) APPCA3CA14CA12CA2
SCHEMBL21903464 0.78 APP (0.75) APPCA3CA14CA12CA2
SCHEMBL241059 0.77 CA2 (0.46) APPCA3CA14CA12CA2
SCHEMBL14173227 0.77 CA2 (0.84) APPCA3CA14CA12CA2
SCHEMBL5495027 0.76 APP (0.47) APPCA3CA14CA12CA2
SCHEMBL14400752 0.76 ESR1 (0.65) APPCA3CA14CA12CA2
SCHEMBL12711690 0.76 ESR1 (0.65) APPCA3CA14CA12CA2
SCHEMBL241974 0.75 APP (0.36) APPMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8231941-B2 Procedure for preparing redox-active polymers on surfaces THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-07-31 US claimed
US-20100330284-A1 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2010-12-30 US claimed
US-7452572-B1 Procedure for preparing redox-active polymers on surfaces THE NORTH CAROLINA STATE UNIVERSITY (US) 2008-11-18 US claimed
US-20080280047-A1 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2008-11-13 US claimed
US-7312100-B2 In situ patterning of electrolyte for molecular information storage devices THE NORTH CAROLINA STATE UNIVERSITY (US) 2007-12-25 US claimed
EP-1809473-A2 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2007-07-25 EP claimed
WO-2005086826-A2 PROCEDURE FOR PREPARING REDOX-ACTIVE POLYMERS ON SURFACES THE REGENTS OF THE UNIVERSITY (US) 2005-09-22 WO claimed
US-20050207208-A1 Situ patterning of electrolyte for molecular information storage devices THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2005-09-22 US claimed
US-6944047-B2 Variable-persistence molecular memory devices and methods of operation thereof NORTH CAROLINA STATE UNIVERSITY (US) 2005-09-13 US claimed
US-20040120180-A1 Variable-persistence molecular memory devices and methods of operation thereof NORTH CAROLINA STATE UNIVERSITY 2004-06-24 US claimed
US-6728129-B2 Multistate triple-decker dyads in three distinct architectures for information storage applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-04-27 US claimed
US-20030169618-A1 Multistate triple-decker dyads in three distinct architectures for information storage applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER 2003-09-11 US claimed
WO-2003071552-A1 MULTISTATE TRIPLE-DECKER DYADS IN THREE DISTINCT ARCHITECTURES FOR INFORMATION STORAGE APPLICATIONS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-08-28 WO claimed
CN-117881432-A Porphyrin-hydrogen porphyrin compounds, compositions comprising the same, and methods of use thereof 北卡罗莱纳州立大学 2024-04-12 CN disclosed
EP-4319823-A1 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF North Carolina State University (US) 2024-02-14 EP disclosed
WO-2022216927-A9 PORPHYRIN-HYDROPORPHYRIN COMPOUNDS, COMPOSITIONS COMPRISING THE SAME AND METHODS OF USE THEREOF NORTH CAROLINA STATE UNIVERSITY (US) 2023-09-14 WO disclosed
US-20030111670-A1 Method and system for molecular charge storage field effect transistor THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-06-19 US disclosed
WO-2003038886-A1 FORMATION OF SELF-ASSEMBLED MONOLAYERS ON SILICON SUBSTRATES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2003-05-08 WO disclosed
US-20030081463-A1 Formation of self-assembled monolayers of redox sams on silicon for molecular memory applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-05-01 US disclosed
US-20030082444-A1 Molehole embedded 3-D crossbar architecture used in electrochemical molecular memory device THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2003-05-01 US disclosed