Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 7/20 | 0.74 |
| ▸ | CA3 | P07451 | 3/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | CA2 | P00918 | 2/20 | 0.58 |
| ▸ | CA9 | Q16790 | 2/20 | 0.58 |
| ▸ | CA6 | P23280 | 2/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14400750 | 1.00 | APP (0.74) | APPCA3CA14CA12CA2 | |
| SCHEMBL21903464 | 0.94 | APP (0.75) | APPCA3CA14CA12CA2 | |
| SCHEMBL12711690 | 0.91 | ESR1 (0.65) | APPCA3CA14CA12CA2 | |
| SCHEMBL14400752 | 0.91 | ESR1 (0.65) | APPCA3CA14CA12CA2 | |
| SCHEMBL18549484 | 0.88 | APP (0.67) | APPCA3CA14CA12CA2 | |
| SCHEMBL673158 | 0.88 | APP (0.61) | APPCA3CA14CA12CA2 | |
| SCHEMBL717647 | 0.88 | APP (0.67) | APPCA3CA14CA12CA2 | |
| SCHEMBL10411992 | 0.87 | APP (0.59) | APPCA3CA14CA12CA2 | |
| SCHEMBL7889999 | 0.86 | ACHE (0.68) | APPCA3CA14CA12CA2 | |
| SCHEMBL15014195 | 0.86 | APP (0.65) | APPCA3CA14CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 319 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3280402-B1 | TOLAN COMPOUNDS FOR PROMOTING WOUND HEALING | BIOMENDICS LLC (US) | 2024-06-05 | — | — | EP | claimed |
| US-11786481-B2 | Formulation and process for modulating wound healing | BioMendics, LLC (US) | 2023-10-17 | — | — | US | claimed |
| US-11351126-B2 | Substituted tolans for the modulation of microbial colonization | BioMendics, LLC (US) | 2022-06-07 | — | — | US | claimed |
| US-20210228501-A1 | Formulation and Process for Modulating Wound Healing | BioMendics, LLC (US) | 2021-07-29 | — | — | US | claimed |
| CN-111526873-A | Substituted tolanes for regulating microbial colonization | 生物曼迪克斯有限责任公司 | 2020-08-11 | — | — | CN | claimed |
| US-20200206154-A1 | Substituted Tolans for the Modulation of Microbial Colonization | BioMendics, LLC (US) | 2020-07-02 | — | — | US | claimed |
| EP-3658128-A1 | SUBSTITUTED TOLANS FOR THE MODULATION OF MICROBIAL COLONIZATION | Biomendics, LLC (US) | 2020-06-03 | — | — | EP | claimed |
| US-10426742-B2 | Formulation and process for modulating wound healing | BioMendics, LLC (US) | 2019-10-01 | — | — | US | claimed |
| WO-2019023425-A1 | SUBSTITUTED TOLANS FOR THE MODULATION OF MICROBIAL COLONIZATION | BioMendics, LLC (US) | 2019-01-31 | — | — | WO | claimed |
| US-20190022029-A1 | Formulation and Process for Modulating Wound Healing | BioMendics, LLC (US) | 2019-01-24 | — | — | US | claimed |
| US-6599945-B2 | Administering a hydroxylated tolan to the host cell of a patient having or suspected having an infection induced by herpes virus | NORTHEASTERN OHIO UNIVERSITIES COLLEGE OF MEDICINE | 2003-07-29 | — | — | US | claimed |
| US-6054193-A | VERY SHORT RESPONSE TIMES, LARGE OPERATING TEMPERATURE RANGE, HIGH CHARACTERISTIC LINE STEEPNESS, GOOD ANGLE DEPENDENCE OF THE CONTRAST AND LOW THRESHOLD VOLTAGE USING A MIXTURE OF LIQUID CRYSTALS ONE OF WHICH CONTAINS A TOLAN-4,4'-DIYL UNIT | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-04-25 | — | — | US | claimed |
| EP-0379058-B1 | Vinyl ester resins containing mesogenic/rigid rodlike moieties | DOW CHEMICAL CO (US) | 1999-09-29 | — | — | EP | claimed |
| US-5702640-A | CONTAINING NEMATIC LIQUID CRYSTAL MIXTURE INCLUDING AT LEAST THREE DIPHENYLACETYLENE COMPOUNDS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1997-12-30 | — | — | US | claimed |
| US-5342904-A | Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties | THE DOW CHEMICAL COMPANY (US) | 1994-08-30 | — | — | US | claimed |
| US-5235008-A | Curable | THE DOW CHEMICAL COMPANY (US) | 1993-08-10 | — | — | US | claimed |
| US-5182340-A | Molding materials having shorter gel time with aliphatic amine curing agents | THE DOW CHEMICAL COMPANY (US) | 1993-01-26 | — | — | US | claimed |
| US-5164464-A | Liquid crystalline polymers, acrylated epoxy resins | THE DOW CHEMICAL COMPANY (US) | 1992-11-17 | — | — | US | claimed |
| US-4962163-A | ADVANCED POLYEPOXIDES AND EPOXY RESINS MODIFIED BY AN UNSATURATED CARBOXYLIC ACID; CURED COATING AND FILMS HAVINGI IMPROVED TENSILE AND FLEXURAL STRENGTH AND MODULUS | THE DOW CHEMICAL COMPANY (US) | 1990-10-09 | — | — | US | claimed |
| EP-0379058-A2 | Vinyl ester resins containing mesogenic/rigid rodlike moieties | THE DOW CHEMICAL COMPANY (US) | 1990-07-25 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11786481-B2 | Formulation and process for modulating wound healing | SQSTM1, ATG7, TFEB | APP 4010/4885CA3 4568/4885CA14 4695/4885 |
| US-20200206154-A1 | Substituted Tolans for the Modulation of Microbial Colonization | LMAN1, DPM1, DSTN | APP 3466/4885CA3 4790/4885CA14 4768/4885 |
| US-20210228501-A1 | Formulation and Process for Modulating Wound Healing | ATG7, SQSTM1, ATF4 | APP 3850/4885CA3 4323/4885CA14 4749/4885 |
| US-10426742-B2 | Formulation and process for modulating wound healing | SQSTM1, ATG7, TFEB | APP 4010/4885CA3 4568/4885CA14 4695/4885 |
| US-20190022029-A1 | Formulation and Process for Modulating Wound Healing | SQSTM1, ATG7, TFEB | APP 4010/4885CA3 4568/4885CA14 4695/4885 |
| US-11351126-B2 | Substituted tolans for the modulation of microbial colonization | LMAN1, DPM1, DSTN | APP 3466/4885CA3 4790/4885CA14 4768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.