Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7758538 | 0.98 | ALDH1A1 (0.37) | ALDH1A1ATMNCF1TSHRCRHBP | |
| Quinoxaline SCHEMBL5268892 | 0.96 | ALDH1A1 (0.35) | ALDH1A1ATMNCF1TSHRCRHBP | |
| SCHEMBL29364156 | 0.85 | ALDH1A1 (0.41) | ALDH1A1ATMTSHRLMNAHTT | |
| SCHEMBL247478 | 0.85 | ALDH1A1 (0.41) | ALDH1A1ATMTSHRLMNAHTT | |
| SCHEMBL5894630 | 0.75 | METAP1 (0.32) | — | |
| SCHEMBL1747903 | 0.75 | KDM4A (0.31) | — | |
| SCHEMBL1015423 | 0.74 | NUDT1 (0.31) | TSHRLMNAHTTKDM4EMAPT | |
| SCHEMBL9317055 | 0.74 | ALDH1A1 (0.38) | ALDH1A1NCF1TSHR | |
| Quinoline SCHEMBL28190534 | 0.74 | ALDH1A1 (0.59) | ALDH1A1ATMTSHRLMNAHTT | |
| SCHEMBL5894455 | 0.72 | ALDH1A1 (0.41) | ALDH1A1ATMTSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2168 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025287-A | Method for catalyzing coupling reaction of quinoxalinone and derivative thereof and electrophile by using lithium silicon amide | 苏州大学 | 2025-05-23 | — | — | CN | claimed |
| CN-119930528-A | Heterogeneous synthesis method of chiral quinoxalinone and derivative thereof | 深圳连续制药科技有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119913525-A | Electrochemical synthesis method of 3-aryl quinoxalinone compound | 新疆大学 | 2025-05-02 | — | — | CN | claimed |
| CN-119874694-A | Quinoxalinone derivative targeting poly ADP ribose polymerase and androgen receptor, and preparation method and application thereof | 无锡市觉新生物科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119663301-A | Preparation method and application of C3-cyanoalkyl substituted quinoxalinone | 安阳工学院 | 2025-03-21 | — | — | CN | claimed |
| CN-119431254-A | Deuterated quinoxalinone diaryl methane compound and synthetic method and application thereof | 重庆文理学院 | 2025-02-14 | — | — | CN | claimed |
| CN-119390699-A | Synthesis method of pyrrolo [1,2-a ] quinoxaline-4 (5H) -ketone compound | 重庆文理学院 | 2025-02-07 | — | — | CN | claimed |
| CN-119143683-A | Quinoxalinone diaryl methane compound and synthetic method and application thereof | 重庆文理学院 | 2024-12-17 | — | — | CN | claimed |
| CN-116120246-B | 3-Butyl-2 (1H) quinoxalinone compound and preparation method thereof | 常州大学 | 2024-11-19 | — | — | CN | claimed |
| CN-118874395-A | Novel synthesis system of quinoxalinone compound | 江苏食品药品职业技术学院 | 2024-11-01 | — | — | CN | claimed |
| EP-0449295-B1 | Novel quinoxalinone derivative | BIO SENSOR KENKYUSHO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | claimed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | claimed |
| EP-0549594-B1 | (2-IMIDAZOLIN-2-YLAMINO) QUINOXALINE DERIVATIVES AND METHODS FOR USING SAME | ALLERGAN INC (US) | 1995-02-01 | — | — | EP | claimed |
| EP-0584222-A4 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE | RHONE POULENC RORER INT (US) | 1994-07-06 | — | — | EP | claimed |
| US-5324835-A | Useful as luminescent labelling reagents or reagents for determining hydrogen peroxide | BIOSENSOR LABORATORIES CO., LTD. (JP) | 1994-06-28 | — | — | US | claimed |
| EP-0584222-A1 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE. | RHONE POULENC RORER INT (US) | 1994-03-02 | — | — | EP | claimed |
| WO-1992020642-A1 | BIS MONO-AND BICYCLIC ARYL AND HETEROARYL COMPOUNDS WHICH INHIBIT EGF AND/OR PDGF RECEPTOR TYROSINE KINASE | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1992-11-26 | — | — | WO | claimed |
| EP-0449295-A1 | Novel quinoxalinone derivative | BIOSENSOR LABORATORIES CO., LTD. (JP) | 1991-10-02 | — | — | EP | claimed |
| EP-0118982-A1 | Organic phosphorous quinoxalinone and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-09-19 | — | — | EP | claimed |