Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HTR1B | P28222 | 2/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 4/20 | 0.33 |
| ▸ | PPARA | Q07869 | 4/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2406181 | 0.74 | ACP3 (0.42) | SIGMAR1HTR1B | |
| SCHEMBL5952980 | 0.72 | KCNA3 (0.41) | SIGMAR1SLC6A4KCNA3CYP1A2 | |
| SCHEMBL5951630 | 0.67 | KDM4E (0.39) | HTR1BCYP1A2CYP2C19 | |
| SCHEMBL1265002 | 0.65 | ALDH1A1 (0.50) | SIGMAR1HTR1BHTR1DCYP1A2CYP2D6 | |
| SCHEMBL30155141 | 0.65 | ALDH1A1 (0.50) | SIGMAR1HTR1BHTR1DCYP1A2CYP2D6 | |
| SCHEMBL1477784 | 0.62 | ALDH1A1 (0.42) | KCNA3CYP1A2CYP2C19 | |
| SCHEMBL24012376 | 0.61 | ALDH1A1 (0.48) | SIGMAR1CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL5601608 | 0.61 | ALDH1A1 (0.48) | SIGMAR1CYP1A2 | |
| SCHEMBL29391558 | 0.61 | ALDH1A1 (0.48) | SIGMAR1CYP1A2 | |
| SCHEMBL29555556 | 0.61 | ALDH1A1 (0.48) | SIGMAR1CYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853424-B2 | Protein cross-linking inhibitor | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2014-10-07 | — | — | US | disclosed |
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2011-09-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110212919-A1 | PROTEIN CROSS-LINKING INHIBITOR | BAZ2B, PRMT1, BRIX1 | SIGMAR1 2136/4885SLC6A4 4662/4885SLC6A3 4461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.